Andrea Grosso1, Marco Pellegrini, Matteo G Cereda, Claudio Panico, Giovanni Staurenghi, Eric J Sigler. 1. *Department of Ophthalmology, Torino Eye Hospital and Centre for Macular Research and Allied Diseases, San Mauro, Italy; †Department of Biomedical and Clinical Science "Luigi Sacco", Eye Clinic, Sacco Hospital, University of Milan, Milan, Italy; ‡Department of Ophthalmology, Torino Eye Hospital, Torino, Italy; §Ophthalmic Consultants of Long Island, Division of Retina and Vitreous, Rockville Centre, New York; and ¶Ophthalmic Consultants of Long Island, Division of Retina and Vitreous, Lynbrook, New York.
Abstract
PURPOSE: To review current literature on Coats disease and provide a structured framework for differentiating challenging clinical features in Coats disease patients. METHODS: We critically reappraise historical and current literature and present clinical methods for developing a thorough differential diagnosis and management strategy for Coats disease. RESULTS: Coats disease is a sporadic, usually unilateral condition typically occurring in young males. When untreated, this disorder can lead to total exudative retinal detachment and secondary glaucoma. CONCLUSIONS: Anti-VEGF agents are currently a treatment option in combination with ablative therapy of telangiectatic vessels. Anti-VEGF agents appear particularly useful for patients with extensive areas of exudative retinal detachment, and are an effective treatment option for total retinal detachment.
PURPOSE: To review current literature on Coats disease and provide a structured framework for differentiating challenging clinical features in Coats diseasepatients. METHODS: We critically reappraise historical and current literature and present clinical methods for developing a thorough differential diagnosis and management strategy for Coats disease. RESULTS:Coats disease is a sporadic, usually unilateral condition typically occurring in young males. When untreated, this disorder can lead to total exudative retinal detachment and secondary glaucoma. CONCLUSIONS: Anti-VEGF agents are currently a treatment option in combination with ablative therapy of telangiectatic vessels. Anti-VEGF agents appear particularly useful for patients with extensive areas of exudative retinal detachment, and are an effective treatment option for total retinal detachment.
Authors: Roy Schwartz; Sobha Sivaprasad; Rebecca Macphee; Patricia Ibanez; Pearse A Keane; Michel Michaelides; Sui Chien Wong Journal: Retina Date: 2019-12 Impact factor: 4.256
Authors: Hyun Goo Kang; Jung Dong Kim; Eun Young Choi; Suk Ho Byeon; Sung Soo Kim; Hyoung Jun Koh; Min Kim Journal: Sci Rep Date: 2021-03-17 Impact factor: 4.379