Literature DB >> 2581131

Effect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE).

P Lavia, M Ferraro, A Micheli, G Olivieri.   

Abstract

Experiments were carried out using human lymphocytes from a male donor in order to test the action of 5-azaC treatment on the induction of SCE and chromatid aberrations. The 5-azaC was found to increase the frequency of both baseline and MMC-induced SCEs. Using the same 5-azaC treatment conditions it was found that the frequency of X-ray-induced CA did not increase.

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Year:  1985        PMID: 2581131     DOI: 10.1016/0027-5107(85)90164-2

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  4 in total

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Authors:  I J Fidler
Journal:  Breast Cancer Res Treat       Date:  1987       Impact factor: 4.872

2.  5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate.

Authors:  V K Pathak; H M Temin
Journal:  J Virol       Date:  1992-05       Impact factor: 5.103

3.  Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs.

Authors:  T J McMillan; I R Hart
Journal:  Clin Exp Metastasis       Date:  1986 Oct-Dec       Impact factor: 5.150

4.  The epigenetic origin of aneuploidy.

Authors:  Luis A Herrera; Diddier Prada; Marco A Andonegui; Alfonso Dueñas-González
Journal:  Curr Genomics       Date:  2008-03       Impact factor: 2.236

  4 in total

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