| Literature DB >> 25809763 |
J D Fonseca1, G M Knight2, T D McHugh3.
Abstract
Multidrug-resistant and extensively drug-resistant tuberculosis (TB) represent a major threat to the control of the disease worldwide. The mechanisms and pathways that result in the emergence and subsequent fixation of resistant strains of Mycobacterium tuberculosis are not fully understood and recent studies suggest that they are much more complex than initially thought. In this review, we highlight the exciting new areas of research within TB resistance that are beginning to fill these gaps in our understanding, whilst also raising new questions and providing future directions.Entities:
Keywords: Drug resistance; Molecular mechanisms of resistance; Tuberculosis
Mesh：
Year: 2015 PMID： 25809763 DOI： 10.1016/j.ijid.2015.01.014
Source DB: PubMed Journal: Int J Infect Dis ISSN： 1201-9712 Impact factor: 3.623