Hubert de Boysson1,2, Nicolas Martin Silva3, François Comoz4, Jonathan Boutemy3, Boris Bienvenu3. 1. Department of Internal Medicine, Caen University Hospital, Caen, France. h.deboysson@ch-lisieux.fr. 2. Service de Médecine Interne, CHU côte de Nacre, avenue de la côte de Nacre, BP 95182, 14033, Caen Cedex 9, France. h.deboysson@ch-lisieux.fr. 3. Department of Internal Medicine, Caen University Hospital, Caen, France. 4. Department of Pathology, Caen University Hospital, Caen, France.
Abstract
INTRODUCTION: Vasculitides occurring during parasitic infection are rare and may imply different mechanisms. METHODS: A case report of cutaneous vasculitis and visceral damage during a larva migrans syndrome. RESULTS: We report the case of a 64-year-old man who developed a purpura along with fever, respiratory failure, abdominal pain and myalgia. Immunological screening showed a high titer of both antinuclear antibodies and anti-double-stranded DNA antibodies along with anti-C1q antibodies. Toxocara canis serology returned highly positive with a positive western-blot. The use of antiparasitic drugs in combination with corticosteroids resulted in a dramatic improvement in the patient's condition. CONCLUSIONS: Clinicians should be aware of the systemic complications that may occur during Toxocara canis infection, including vasculitis and immunological disorder.
INTRODUCTION: Vasculitides occurring during parasitic infection are rare and may imply different mechanisms. METHODS: A case report of cutaneous vasculitis and visceral damage during a larva migrans syndrome. RESULTS: We report the case of a 64-year-old man who developed a purpura along with fever, respiratory failure, abdominal pain and myalgia. Immunological screening showed a high titer of both antinuclear antibodies and anti-double-stranded DNA antibodies along with anti-C1q antibodies. Toxocara canis serology returned highly positive with a positive western-blot. The use of antiparasitic drugs in combination with corticosteroids resulted in a dramatic improvement in the patient's condition. CONCLUSIONS: Clinicians should be aware of the systemic complications that may occur during Toxocara canis infection, including vasculitis and immunological disorder.
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