Literature DB >> 25806906

Additives to local anesthetics for peripheral nerve blocks or local anesthesia: a review of the literature.

Mathias Opperer1, Peter Gerner, Stavros G Memtsoudis.   

Abstract

A multitude of studies have focused on individual additives to local anesthetics and their effect on quality, onset, duration, spread and selectivity, as well as the potential toxic effects of their use. This review aims to give a broad overview of the current evidence in this developing field, based on beneficial and adverse effects of these drugs. We discuss the limitations of the available data and hope to convey implications and future perspectives for clinicians and researchers alike.

Keywords:  additives; analgesic duration; analgesic quality; block onset; local anesthesia; local anesthetics; neurotoxicity; nociceptive selectivity; peripheral nerve block

Mesh：

Substances：

Year:  2015        PMID： 25806906     DOI： 10.2217/pmt.15.2

Source DB:  PubMed          Journal:  Pain Manag        ISSN： 1758-1869


  8 in total

1.  Low-dose NSAIDs reduce pain via macrophage targeted nanoemulsion delivery to neuroinflammation of the sciatic nerve in rat.

Authors:  Jelena M Janjic; Kiran Vasudeva; Muzamil Saleem; Andrea Stevens; Lu Liu; Sravan Patel; John A Pollock
Journal:  J Neuroimmunol       Date:  2018-02-25       Impact factor: 3.478

2.  Intrathecal pramipexole and selegiline for sensory and motor block in rats.

Authors:  Chun-Chang Yeh; An-Kuo Chou; Yu-Wen Chen; Ching-Hsia Hung; Chong-Chi Chiu; Jhi-Joung Wang; Guan-Cheng Zhu
Journal:  Pharmacol Rep       Date:  2022-05-13       Impact factor: 3.024

Review 3.  Dexmedetomidine combined with local anesthetics in thoracic paravertebral block: A systematic review and meta-analysis of randomized controlled trials.

Authors:  Kai Wang; Li-Jun Wang; Tong-Jiu Yang; Qing-Xiang Mao; Zhen Wang; Li-Yong Chen
Journal:  Medicine (Baltimore)       Date:  2018-11       Impact factor: 1.817

Review 4.  Review of adjuvants to local anesthetics in peripheral nerve blocks: Current and future trends.

Authors:  G V Krishna Prasad; Sangeeta Khanna; Sharma Vipin Jaishree
Journal:  Saudi J Anaesth       Date:  2020-01-06

5.  Evidence basis for using dexmedetomidine to enhance the quality of paravertebral block: A systematic review and meta-analysis of randomized controlled trials.

Authors:  Rong Tang; Yu-Qian Liu; Hai-Lian Zhong; Fang Wu; Shi-Xiong Gao; Wei Liu; Wen-Sheng Lu; Ying-Bin Wang
Journal:  Front Pharmacol       Date:  2022-09-29       Impact factor: 5.988

6.  Off-label use of drugs in regional anesthesia: A need for setting up policies.

Authors:  Saru Singh; Pranav Bansal; Jagdish Dureja
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2017 Oct-Dec

Review 7.  Sleep Disturbances After General Anesthesia: Current Perspectives.

Authors:  Man Luo; Bijia Song; Junchao Zhu
Journal:  Front Neurol       Date:  2020-07-08       Impact factor: 4.003

8.  Does local anesthetic temperature affect the onset and duration of ultrasound-guided infraclavicular brachial plexus nerve block?: a randomized clinical trial.

Authors:  Ilker Ince; Muhammed Ali Arı; Aysenur Dostbil; Esra Kutlu Yalcin; Ozgur Ozmen; M Zafeer Khan; Tetsuya Shimada; Mehmet Aksoy; Kutsi Tuncer
Journal:  Braz J Anesthesiol       Date:  2021-04-03
  8 in total

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