Literature DB >> 25806309

Coexistent pulmonary granular cell tumor and adenocarcinoma of the lung.

Vyshak Alva Venur1, Gloria Zhang1, Carol Farver1, Sanjay Mukhopadhyay1, Daniel P Raymond1, Vamsidhar Velcheti1.   

Abstract

We report a case of granular cell tumor (GCT) of the lung with coexistent invasive adenocarcinoma. GCTs are rare tumors and often benign and amenable to local bronchoscopic excision. However, occasionally they are more aggressive and locally infiltrative requiring definitive surgical resection. Our patient had a central and infiltrative GCT, in addition a very small (6 mm) peripheral nodule in the same lobe as the GCT, which after careful examination of the surgical specimen during grossing was found to be an invasive adenocarcinoma. There are a few reports in the literature of GCTs with coexistent bronchogenic cancer. Our case highlights the importance of careful evaluation and exploration of the surgical specimens during grossing of patients with GCTs. In GCT patients presenting with additional pulmonary nodules, a more definitive surgical approach should be considered.

Entities:  

Keywords:  Granular cell tumor (GCT); coexistent adenocarcinoma; non-small cell lung cancer

Year:  2014        PMID: 25806309      PMCID: PMC4367698          DOI: 10.3978/j.issn.2218-6751.2014.06.03

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN: 2218-6751


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  1 in total

1.  Clinicopathological characteristics and gene analysis of pulmonary granular cell tumor in three cases and a systematic review.

Authors:  Hai Zhang; Fang Hu; Xueyan Zhang; Yanwei Zhang; Changhui Li; Yuqing Chen; Feng Li
Journal:  Transl Cancer Res       Date:  2020-08       Impact factor: 1.241

  1 in total

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