Literature DB >> 25806305

Radiotherapy for single station N2 NSCLC.

Jan P van Meerbeeck1.   

Abstract

Clinical 'single station N2' is a prognostic factor, which is only moderately identifiable preoperatively, even after adequate mediastinal staging. There is little evidence that 'single station N2' predicts for the outcome of any radical treatment strategy, or for a benefit of postoperative radiotherapy. In adequately staged patients with clinical 'single station N2' involvement, modern definitive chemoradiation therapy results in equivalent outcome as induction therapy followed by resection.

Entities:  

Keywords:  N2; Radiotherapy; lung cancer; stage IIIA

Year:  2014        PMID: 25806305      PMCID: PMC4367705          DOI: 10.3978/j.issn.2218-6751.2014.07.04

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN: 2218-6751


  29 in total

1.  A randomized trial of postoperative adjuvant therapy in patients with completely resected stage II or IIIA non-small-cell lung cancer. Eastern Cooperative Oncology Group.

Authors:  S M Keller; S Adak; H Wagner; A Herskovic; R Komaki; B J Brooks; M C Perry; R B Livingston; D H Johnson
Journal:  N Engl J Med       Date:  2000-10-26       Impact factor: 91.245

2.  What now for postoperative radiotherapy for lung cancer?

Authors:  A J Munro
Journal:  Lancet       Date:  1998-07-25       Impact factor: 79.321

3.  Overall survival and local recurrence of 406 completely resected stage IIIa-N2 non-small cell lung cancer patients: questionnaire survey of the Japan Clinical Oncology Group to plan for clinical trials.

Authors:  Y Ichinose; H Kato; T Koike; R Tsuchiya; T Fujisawa; N Shimizu; Y Watanabe; T Mitsudomi; M Yoshimura
Journal:  Lung Cancer       Date:  2001-10       Impact factor: 5.705

4.  Postoperative radiotherapy for stage II or III non-small-cell lung cancer using the surveillance, epidemiology, and end results database.

Authors:  Brian E Lally; Daniel Zelterman; Joseph M Colasanto; Bruce G Haffty; Frank C Detterbeck; Lynn D Wilson
Journal:  J Clin Oncol       Date:  2006-06-12       Impact factor: 44.544

5.  Long-term survival of surgically staged IIIA-N2 non-small-cell lung cancer treated with surgical combined modality approach: analysis of a 7-year prospective experience.

Authors:  N Lorent; P De Leyn; Y Lievens; E Verbeken; K Nackaerts; C Dooms; D Van Raemdonck; B Anrys; J Vansteenkiste
Journal:  Ann Oncol       Date:  2004-11       Impact factor: 32.976

6.  Post-operative radiotherapy (PORT) or chemoradiotherapy (CPORT) following resection of stages II and IIIA non-small cell lung cancer (NSCLC) does not increase the expected risk of death from intercurrent disease (DID) in Eastern Cooperative Oncology Group (ECOG) trial E3590.

Authors:  Heather A Wakelee; Patricia Stephenson; Steven M Keller; Henry Wagner; Arnold Herskovic; Ritsuko Komaki; Randolph S Marks; Michael C Perry; Robert B Livingston; David H Johnson
Journal:  Lung Cancer       Date:  2005-01-05       Impact factor: 5.705

7.  Postoperative radiotherapy for patients with completely resected pathological stage IIIA-N2 non-small cell lung cancer: focusing on an effect of the number of mediastinal lymph node stations involved.

Authors:  Haruhisa Matsuguma; Rie Nakahara; Yoshinori Ishikawa; Haruko Suzuki; Koichi Inoue; Susumu Katano; Kohei Yokoi
Journal:  Interact Cardiovasc Thorac Surg       Date:  2008-04-15

Review 8.  Postoperative radiotherapy in stage II or IIIA completely resected non-small cell lung cancer: a systematic review and practice guideline.

Authors:  Gordon Okawara; Yee Chung Ung; Barbara R Markman; Jean A Mackay; William K Evans
Journal:  Lung Cancer       Date:  2004-04       Impact factor: 5.705

9.  Treatment of stage III non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

Authors:  Nithya Ramnath; Thomas J Dilling; Loren J Harris; Anthony W Kim; Gaetane C Michaud; Alex A Balekian; Rebecca Diekemper; Frank C Detterbeck; Douglas A Arenberg
Journal:  Chest       Date:  2013-05       Impact factor: 9.410

10.  A closer look at the effects of postoperative radiotherapy by stage and nodal status: updated results of an individual participant data meta-analysis in non-small-cell lung cancer.

Authors:  Sarah Burdett; Larysa Rydzewska; Jayne F Tierney; David J Fisher
Journal:  Lung Cancer       Date:  2013-02-27       Impact factor: 5.705

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