Literature DB >> 25806295

Is surgery still the best management option for early stage NSCLC?

Aurel Ottlakan1, Nicola Martucci1, Gaetano Rocco1.   

Abstract

Under the formidable thrust of alternative management options for early stage lung cancer, the role of surgery in this disease subset has been questioned. Stereotactic body radiotherapy (SBRT) has been advocated as an ideal substitute for surgery not only in high risk patients or for the ones who refuse surgery but also in lieu of sublobar resection in otherwise fit patients. The therapeutic modalities for early stage NSCLC were compared as to warranting local control, enabling adequate tissue sampling for biomolecular studies, and effecting optimal pathologic staging while saving lung parenchyma. As a result, surgery still remains the best management option for early stage lung cancer in 2014.

Entities:  

Keywords:  Lung cancer; stereotactic body radiotherapy (SBRT); surgery

Year:  2014        PMID: 25806295      PMCID: PMC4367695          DOI: 10.3978/j.issn.2218-6751.2014.06.05

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN: 2218-6751


  31 in total

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Journal:  Thorac Surg Clin       Date:  2011-10-12       Impact factor: 1.750

2.  Uniportal VATS for mediastinal nodal diagnosis and staging.

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3.  Ten-year experience on 644 patients undergoing single-port (uniportal) video-assisted thoracoscopic surgery.

Authors:  Gaetano Rocco; Nicola Martucci; Carmine La Manna; David R Jones; Giuseppe De Luca; Antonello La Rocca; Arturo Cuomo; Rosanna Accardo
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4.  When is a biopsy-proven diagnosis necessary before stereotactic ablative radiotherapy for lung cancer?: A decision analysis.

Authors:  Alexander V Louie; Suresh Senan; Pretesh Patel; Bart S Ferket; Frank J Lagerwaard; George B Rodrigues; Joseph K Salama; Christopher Kelsey; David A Palma; Myriam G Hunink
Journal:  Chest       Date:  2014-10       Impact factor: 9.410

5.  The surgeon's role in molecular biology.

Authors:  Gaetano Rocco
Journal:  J Thorac Cardiovasc Surg       Date:  2012-06-26       Impact factor: 5.209

6.  Comparative effectiveness of 5 treatment strategies for early-stage non-small cell lung cancer in the elderly.

Authors:  Shervin M Shirvani; Jing Jiang; Joe Y Chang; James W Welsh; Daniel R Gomez; Stephen Swisher; Thomas A Buchholz; Benjamin D Smith
Journal:  Int J Radiat Oncol Biol Phys       Date:  2012-09-11       Impact factor: 7.038

7.  Comparison of endobronchial ultrasound and/or endoesophageal ultrasound with transcervical extended mediastinal lymphadenectomy for staging and restaging of non-small-cell lung cancer.

Authors:  Marcin Zielinski; Artur Szlubowski; Marcin Kołodziej; Stanislaw Orzechowski; Ewa Laczynska; Juliusz Pankowski; Magdalena Jakubiak; Anna Obrochta
Journal:  J Thorac Oncol       Date:  2013-05       Impact factor: 15.609

8.  Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer.

Authors:  Paul De Leyn; Christophe Dooms; Jaroslaw Kuzdzal; Didier Lardinois; Bernward Passlick; Ramon Rami-Porta; Akif Turna; Paul Van Schil; Frederico Venuta; David Waller; Walter Weder; Marcin Zielinski
Journal:  Eur J Cardiothorac Surg       Date:  2014-02-26       Impact factor: 4.191

9.  Video-assisted mediastinoscopic lymphadenectomy (VAMLA)--a method for systematic mediastinal lymphnode dissection.

Authors:  Gunda Leschber; Gabriele Holinka; Albert Linder
Journal:  Eur J Cardiothorac Surg       Date:  2003-08       Impact factor: 4.191

10.  Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling.

Authors:  Humam Kadara; Li Shen; Junya Fujimoto; Pierre Saintigny; Chi-Wan Chow; Wenhua Lang; Zuoming Chu; Melinda Garcia; Mohamed Kabbout; You-Hong Fan; Carmen Behrens; Diane A Liu; Li Mao; J Jack Lee; Kathryn A Gold; Jing Wang; Kevin R Coombes; Edward S Kim; Waun Ki Hong; Ignacio I Wistuba
Journal:  Cancer Prev Res (Phila)       Date:  2012-10-19
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  3 in total

Review 1.  Current and future targeted therapies for non-small-cell lung cancers with aberrant EGF receptors.

Authors:  Shanthi Kanthala; Sandeep Pallerla; Seetharama Jois
Journal:  Future Oncol       Date:  2015       Impact factor: 3.404

Review 2.  Stereotactic body radiotherapy (SBRT) for the treatment of inoperable stage I non-small cell lung cancer patients.

Authors:  L Ceniceros; J Aristu; E Castañón; C Rolfo; J Legaspi; A Olarte; G Valtueña; M Moreno; I Gil-Bazo
Journal:  Clin Transl Oncol       Date:  2015-08-05       Impact factor: 3.405

3.  [Efficacy of Stereotactic Body Radiotherapy versus Surgery for the Treatment 
of Early Non-small Cell Lung Cancer: A Meta-analysis].

Authors:  Qiangbin Wu; Wanpeng Gao; Jiawang Zhu; Qiang Wang; Wei Zhang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2020-12-20
  3 in total

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