Li Wang1, Yong Song1, Guan-Nan Wu1, Dong-Mei Yuan1. 1. Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, P. R. China.
Abstract
OBJECTIVE: To assess the correlation between metformin and risk of developing lung cancer by meta-analysis. METHODS: Papers on the correlation between metformin and risk of lung cancer were searched from PubMed, MEDLINE, EMBASE, ISI Web of Science, and Cochrane Library. RESULTS: Six papers on case-control study were included in this study, involving 39,787 metformin users and 177,752 controls. Meta-analysis showed that the risk of developing lung cancer was lower in metformin users than in those without metformin (OR=0.55, 95% CI: 0.35-0.85, P<0.001). CONCLUSIONS: The risk of developing lung cancer is lower in metformin users than in those without metformin.
OBJECTIVE: To assess the correlation between metformin and risk of developing lung cancer by meta-analysis. METHODS: Papers on the correlation between metformin and risk of lung cancer were searched from PubMed, MEDLINE, EMBASE, ISI Web of Science, and Cochrane Library. RESULTS: Six papers on case-control study were included in this study, involving 39,787 metformin users and 177,752 controls. Meta-analysis showed that the risk of developing lung cancer was lower in metformin users than in those without metformin (OR=0.55, 95% CI: 0.35-0.85, P<0.001). CONCLUSIONS: The risk of developing lung cancer is lower in metformin users than in those without metformin.
Authors: M B Schneider; H Matsuzaki; J Haorah; A Ulrich; J Standop; X Z Ding; T E Adrian; P M Pour Journal: Gastroenterology Date: 2001-04 Impact factor: 22.682
Authors: Craig J Currie; Chris D Poole; Sara Jenkins-Jones; Edwin A M Gale; Jeffrey A Johnson; Christopher Ll Morgan Journal: Diabetes Care Date: 2012-01-20 Impact factor: 19.112