Literature DB >> 25806159

Updating advances on recombinant human endostatin combined with radiotherapy for non-small cell lung cancer with brain metastasis.

Xiao-Dong Jiang1, Yun Qiao1.   

Abstract

Brain metastases (BM) heavily affects the prognosis of advanced non-small cell lung cancer (NSCLC). Although whole-brain radiotherapy remains the mainstream therapy for BM caused by NSCLC, the effectiveness is unsatisfactory. Endostar, a recombinant human endostatin (RHES), has shown certain therapeutic effect on advanced NSCLC. This article reviews the feasibility of Endostar combined with radiotherapy in the treatment of BM caused by NSCLC.

Entities:  

Keywords:  Brain metastases; Non-small cell lung cancer; Radiotherapy; Recombinant human endostatin (Endostar)

Year:  2012        PMID： 25806159      PMCID： PMC4367588          DOI： 10.3978/j.issn.2218-6751.2011.12.06

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN： 2218-6751


  38 in total

1.  Radiation-enhanced endostatin gene expression and effects of combination treatment.

Authors:  Xian Luo; Melba L Andres; Tatyana M Timiryasova; Istvan Fodor; James M Slater; Daila S Gridley
Journal:  Technol Cancer Res Treat       Date:  2005-04

2.  A cancer drug shows promise, at a price that many can't pay.

Authors:  Alex Berenson
Journal:  N Y Times Web       Date:  2006-02-15

3.  [Combined effects of endostatin gene transfer and ionizing radiation on lung adenocarcinoma model of A549-cells].

Authors:  Chun-hua Ling; Cheng Ji; Yan-bin Chen; Jian-xin Fu; Ju-ying Zhou; Wei-chang Chen; Ji-cheng Yang; Liao-yuan Su
Journal:  Zhonghua Jie He He Hu Xi Za Zhi       Date:  2004-10

Review 4.  Vascular endothelial growth factor and vascular targeting of solid tumors.

Authors:  R A Brekken; P E Thorpe
Journal:  Anticancer Res       Date:  2001 Nov-Dec       Impact factor: 2.480

5.  Squamous cell head and neck cancer: evidence of angiogenic regeneration during radiotherapy.

Authors:  M I Koukourakis; A Giatromanolaki; E Sivridis; K Simopoulos; G Pissakas; K C Gatter; A L Harris
Journal:  Anticancer Res       Date:  2001 Nov-Dec       Impact factor: 2.480

Review 6.  Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy.

Authors:  Rakesh K Jain
Journal:  Science       Date:  2005-01-07       Impact factor: 47.728

7.  Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.

Authors:  C G Lee; M Heijn; E di Tomaso; G Griffon-Etienne; M Ancukiewicz; C Koike; K R Park; N Ferrara; R K Jain; H D Suit; Y Boucher
Journal:  Cancer Res       Date:  2000-10-01       Impact factor: 12.701

8.  SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro.

Authors:  Amir Abdollahi; Kenneth E Lipson; Xiaohong Han; Robert Krempien; Thuy Trinh; Klaus J Weber; Philip Hahnfeldt; Lynn Hlatky; Juergen Debus; Anthony R Howlett; Peter E Huber
Journal:  Cancer Res       Date:  2003-07-01       Impact factor: 12.701

Review 9.  Epidemiology, diagnosis, and treatment of patients with metastatic cancer and high-grade gliomas of the central nervous system.

Authors:  Denise M Lemke
Journal:  J Infus Nurs       Date:  2004 Jul-Aug

Review 10.  VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer.

Authors:  Elizabeth R Gerstner; Dan G Duda; Emmanuelle di Tomaso; Peter A Ryg; Jay S Loeffler; A Gregory Sorensen; Percy Ivy; Rakesh K Jain; Tracy T Batchelor
Journal:  Nat Rev Clin Oncol       Date:  2009-04       Impact factor: 66.675
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.