| Literature DB >> 25805132 |
Valérie Borde1, Bernard de Massy2.
Abstract
During meiotic prophase, the repair of induced DNA double-strand breaks (DSBs) promotes interactions between homologous chromosomes (homologs). A study by Joshi et al. (2015) now highlights how the global DSB activity in a nucleus influences the choice between the homolog and the sister chromatid for DSB repair.Mesh:
Year: 2015 PMID: 25805132 DOI: 10.1016/j.devcel.2015.03.011
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270