| Literature DB >> 25805129 |
Laurence Walch1, Alenka Čopič1, Catherine L Jackson2.
Abstract
Upon nutrient deprivation, cells metabolize fatty acids (FAs) in mitochondria to supply energy, but how FAs, stored as triacylglycerols in lipid droplets, reach mitochondria has been mysterious. Rambold et al. (2015) now show that FA mobilization depends on triacylglycerol lipolysis, whereas autophagy feeds the lipid droplet pool for continued fueling of mitochondria.Entities:
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Year: 2015 PMID： 25805129 DOI： 10.1016/j.devcel.2015.03.008
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270