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Literature DB >> 25804282

Loss of Klotho in CKD Breaks One's Heart.

Haiyan Fu¹, Youhua Liu².

Abstract

Entities: Gene

Keywords: CKD; cardiovascular disease; left ventricular hypertrophy

Mesh：

Substances：
Glucuronidase
Indican

Year: 2015 PMID： 25804282 PMCID： PMC4587709 DOI： 10.1681/ASN.2015020200

Source DB: PubMed Journal: J Am Soc Nephrol ISSN： 1046-6673 Impact factor: 10.121

× No keyword cloud information.

15 in total

Review 1. Klotho in health and disease.

Authors: Makoto Kuro-o
Journal: Curr Opin Nephrol Hypertens Date: 2012-07 Impact factor: 2.894

2. FGF23 induces left ventricular hypertrophy.

Authors: Christian Faul; Ansel P Amaral; Behzad Oskouei; Ming-Chang Hu; Alexis Sloan; Tamara Isakova; Orlando M Gutiérrez; Robier Aguillon-Prada; Joy Lincoln; Joshua M Hare; Peter Mundel; Azorides Morales; Julia Scialla; Michael Fischer; Elsayed Z Soliman; Jing Chen; Alan S Go; Sylvia E Rosas; Lisa Nessel; Raymond R Townsend; Harold I Feldman; Martin St John Sutton; Akinlolu Ojo; Crystal Gadegbeku; Giovana Seno Di Marco; Stefan Reuter; Dominik Kentrup; Klaus Tiemann; Marcus Brand; Joseph A Hill; Orson W Moe; Makoto Kuro-O; John W Kusek; Martin G Keane; Myles Wolf
Journal: J Clin Invest Date: 2011-10-10 Impact factor: 14.808

3. Plasma klotho and cardiovascular disease in adults.

Authors: Richard D Semba; Anne R Cappola; Kai Sun; Stefania Bandinelli; Mansi Dalal; Candace Crasto; Jack M Guralnik; Luigi Ferrucci
Journal: J Am Geriatr Soc Date: 2011-08-24 Impact factor: 5.562

4. Loss of Klotho contributes to kidney injury by derepression of Wnt/β-catenin signaling.

Authors: Lili Zhou; Yingjian Li; Dong Zhou; Roderick J Tan; Youhua Liu
Journal: J Am Soc Nephrol Date: 2013-04-04 Impact factor: 10.121

5. Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice.

Authors: Shigehiro Doi; Yonglong Zou; Osamu Togao; Johanne V Pastor; George B John; Lei Wang; Kazuhiro Shiizaki; Russell Gotschall; Susan Schiavi; Noriaki Yorioka; Masaya Takahashi; David A Boothman; Makoto Kuro-O
Journal: J Biol Chem Date: 2011-01-05 Impact factor: 5.157

Loss of Klotho in CKD Breaks One's Heart.

Review 1. Klotho in health and disease.

2. FGF23 induces left ventricular hypertrophy.

3. Plasma klotho and cardiovascular disease in adults.

4. Loss of Klotho contributes to kidney injury by derepression of Wnt/β-catenin signaling.

5. Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice.

6. Klotho deficiency causes vascular calcification in chronic kidney disease.

7. Klotho Protects Against Indoxyl Sulphate-Induced Myocardial Hypertrophy.

8. Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate.

9. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.

10. Multiple genes of the renin-angiotensin system are novel targets of Wnt/β-catenin signaling.

Review 1. The role of fibroblast growth factor 23 and Klotho in uremic cardiomyopathy.

2. Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome.

Review 3. Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression.