Literature DB >> 25803675

Long-term patient-reported functional and cosmetic outcomes following severe traumatic foot and ankle wound reconstruction with acellular dermal matrix.

Romain Weigert1, Franck Marie Leclere1, Gabriele Delia2, Laura De Luca3, Khalid Al Mutairi1, Vincent Casoli1.   

Abstract

BACKGROUND: The prevalence of acellular dermal matrices in reconstructive surgery has increased through the last decade with satisfying outcomes. Long-term follow-up and effectiveness studies could enable appropriate use of these devices and challenge the current gold-standard treatments. This paper presents functional and cosmetic long-term outcomes on the Integra(®) Dermal Regeneration Template (IDRT) for treating traumatic soft-tissue defects of the foot and ankle.
METHODS: All adult patients who underwent severe traumatic foot and ankle reconstruction with Integra(®) since 2004 were retrospectively included. Results were evaluated using standardized outcome instruments.
RESULTS: Twenty-one reconstructions were evaluated 4.5 ± 2.5 years after foot and ankle injury. Major complications inducing a second application included 1 hematoma and 1 infection. Seven patients (35%) had good or excellent Foot and Ankle Ability Measures. Subjectively, when asked to compare current function with pre-injury status, the mean response was 66 ± 23%. The Observer Scar Assessment Scale scored 17 ± 5 points (possible range, 5-50), while the Patient Scar Assessment Scale scored 30 ± 11 points (possible range, 6-60).
CONCLUSIONS: Long-term functional and cosmetic outcomes 4.5 years after severe traumatic foot and ankle wounds treated with IDRTs were rated fair in the great majority of patients. Nevertheless, because complications and surgical revisions were few, potential benefits might be underestimated because of the initial combined injuries and their sequelae. In this way, for appropriately selected patients with severe traumatic foot and ankle soft-tissue defects, including subacute coverage, it appears that this treatment may be a viable first option.

Entities:  

Keywords:  acellular dermal matrix; ankle; foot; integra; outcomes; traumatic wound

Mesh:

Substances:

Year:  2015        PMID: 25803675     DOI: 10.3109/14764172.2015.1027231

Source DB:  PubMed          Journal:  J Cosmet Laser Ther        ISSN: 1476-4172            Impact factor:   2.247


  3 in total

1.  Long-term follow-up comparison of two different bi-layer dermal substitutes in tissue regeneration: Clinical outcomes and histological findings.

Authors:  Uberto M Giovannini; Luc Teot
Journal:  Int Wound J       Date:  2020-05-02       Impact factor: 3.315

Review 2.  Infectious Complications Associated with the Use of Integra: A Systematic Review of the Literature.

Authors:  Santiago R Gonzalez; Keith G Wolter; James C Yuen
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-07-15

3.  Indications and Limitations of Bilayer Wound Matrix-Based Lower Extremity Reconstruction: A Multidisciplinary Case-Control Study of 191 Wounds.

Authors:  Sameer Shakir; Charles A Messa; Robyn B Broach; Irfan A Rhemtulla; Brett Chatman; Albert D'Angelantonio; L Scott Levin; Stephen J Kovach; Joseph M Serletti; John P Fischer
Journal:  Plast Reconstr Surg       Date:  2020-03       Impact factor: 5.169

  3 in total

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