Colonic Carcinoma Associated with Malakoplakia.

Malakoplakia is an unusual chronic inflammatory response first described in the genitourinary tract by Michaelis and Gutmann in 1902. It is now known to occur in other locations including the gastrointestinal tract, skin, lungs and the central nervous system. Malakoplakia has been frequently misdiagnosed clinically as a malignant lesion. Similarly, when it occurs in the gastrointestinal tract (eg colon) in association with adenocarcinoma, it may lead to clinical and radiological overstaging of the tumour.