Literature DB >> 25803199

The flavan-isoflavan rearrangement: bioinspired synthetic access to isoflavonoids via 1,2-shift-alkylation sequence.

Kayo Nakamura1, Ken Ohmori, Keisuke Suzuki.   

Abstract

An approach to 2-substituted isoflavonoids is reported based on the 1,2-shift of the aryl group in the catechin skeleton followed by the in situ alkylation. Synthesis of (-)-equol, a natural isoflavan with estrogenic activities, was achieved.

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Year:  2015        PMID: 25803199     DOI: 10.1039/c5cc01572c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Synthetic studies towards the penicisulfuranols: Synthesis of an advanced spirocyclic diketopiperazine intermediate.

Authors:  Kevin M Gayler; Kyle M Lambert; John L Wood
Journal:  Tetrahedron       Date:  2019-01-21       Impact factor: 2.457

  1 in total

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