Literature DB >> 25802978

One-pot Sonogashira coupling-cyclization toward regioselective synthesis of benzosultams.

Sudarshan Debnath1, Shovan Mondal1.   

Abstract

A one-pot method for the Sonogashira coupling and cyclization of 2-bromobenzenesulfonamides and terminal alkynes is presented. This method allows access to a variety of substituted benzosultams regioselectively in excellent yields. The reasons for regioselectivity are interpreted through density functional theory (DFT) studies.

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Year:  2015        PMID： 25802978     DOI： 10.1021/acs.joc.5b00274

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

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Journal:  Molecules       Date:  2020-09-23       Impact factor: 4.411

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Authors:  Badr Jismy; Khalil Cherry; Carine Maaliki; Samuel Inack Ngi; Mohamed Abarbri
Journal:  Molecules       Date:  2020-11-04       Impact factor: 4.411
  3 in total

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