Xiaoying Zhang1, Rong Mu1, Xiuru Wang2, Chuanhui Xu1, Tianjiao Duan3, Yuan An1, Shuling Han2, Xiaofeng Li4, Lizhi Wang4, Caihong Wang4, Yongfu Wang5, Rong Yang5, Guochun Wang6, Xin Lu6, Ping Zhu7, Lina Chen7, Jinting Liu8, Hongtao Jin8, Xiangyuan Liu9, Lin Sun9, Ping Wei10, Junxiang Wang10, Haiying Chen10, Liufu Cui11, Rong Shu11, Bailu Liu11, Zhuoli Zhang12, Guangtao Li12, Zhenbin Li13, Jing Yang13, Junfang Li14, Bin Jia14, Fengxiao Zhang15, Jiemei Tao15, Jinying Lin16, Meiqiu Wei16, Xiaomin Liu17, Dan Ke17, Shaoxian Hu18, Cong Ye18, Xiuyan Yang19, Hao Li19, Cibo Huang20, Ming Gao20, Pei Lai20, Xingfu Li21, Lijun Song21, Yi Wang22, Xiaoyuan Wang22, Yin Su1, Zhanguo Li23. 1. Department of Rheumatology and Immunology, People's Hospital, Peking University Health Science Center. 2. Department of Rheumatology and Immunology, Peking University Shougang Hospital. 3. Department of Gastroenterology, People's Hospital, Peking University Health Science Center, Beijing. 4. Department of Rheumatology and Immunology, Second Hospital of Shanxi Medical University, Taiyuan. 5. Department of Rheumatology and Immunology, First Affiliated Hospital, Baotou Medical College, Baotou. 6. Department of Rheumatology, China-Japan Friendship Hospital, Beijing. 7. Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an. 8. Department of Rheumatology and Immunology, Second Hospital of Hebei Medical University, Shijiazhuang. 9. Department of Rheumatology and Immunology, Peking University Third Hospital, Beijing. 10. Department of Rheumatology and Immunology, Third Hospital of Hebei Medical University, Shijiazhuang. 11. Department of Rheumatology and Immunology, Affiliated Kailuan Hospital of North China Coal Medical University, Tangshan, Hebei. 12. Department of Rheumatology and Clinical Immunology, Peking University First Hospital, Beijing. 13. Department of Rheumatology and Immunology, Bethune International Peace Hospital of PLA, Shijiazhuang. 14. Department of Rheumatology and Immunology, Handan Central Hospital, Handan. 15. Department of Rheumatology and Immunology, People's Hospital of Hebei Province, Shijiazhuang. 16. Department of Rheumatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning. 17. Department of Rheumatology and Immunology, Beijing Shunyi Hospital, Beijing. 18. Department of Rheumatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan. 19. Department of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou. 20. Department of Rheumatology and Immunology, Beijing Hospital, Beijing. 21. Department of Rheumatology, Shandong University Qilu Hospital, Jinan and. 22. Deparment of Rheumatology, Second Hospital of Lanzhou University, Lanzhou, China. 23. Department of Rheumatology and Immunology, People's Hospital, Peking University Health Science Center, zgli99@aliyun.com.
Abstract
OBJECTIVE: To evaluate the impact of RA on work capacity and identify factors related to work capacity impairment in patients with RA. METHODS: A cross-sectional multicentre study was performed in 21 tertiary care hospitals across China. A consecutive sample of 846 patients with RA was recruited, of which 589 patients of working age at disease onset constituted the study population. Information on the socio-demographic, clinical, working and financial conditions of the patients was collected. Logistic regression analyses were used to identify factors associated with work capacity impairment. RESULTS: The rate of work capacity impairment was 48.0% in RA patients with a mean disease duration of 60 months (interquartile range 14-134 months), including 11.7% leaving the labour force early, 33.6% working reduced hours and 2.7% changing job. Multivariable logistic regression analysis showed that reduced working hours was significantly related to current smoking [odds ratio (OR) 2.07 (95% CI 1.08, 3.97)], no insurance [OR 1.94 (95% CI 1.20, 3.12)], in manual labour [OR 2.66 (95% CI 1.68, 4.20)] and higher HAQ score [OR 2.22 (95% CI 1.36, 3.60)]. There was an association of current smoking [OR 3.75 (95% CI 1.54, 9.15)], in manual labour [OR 2.33 (95% CI 1.17, 4.64)], longer disease duration [OR 1.01 (95% CI 1.00, 1.01)] and lower BMI [OR 0.90 (95% CI 0.82, 0.99)] with leaving the labour force early. CONCLUSION: There is a substantial impact of RA on the work capacity of patients in China. Social-demographic, disease- and work-related factors are all associated with work capacity impairment.
OBJECTIVE: To evaluate the impact of RA on work capacity and identify factors related to work capacity impairment in patients with RA. METHODS: A cross-sectional multicentre study was performed in 21 tertiary care hospitals across China. A consecutive sample of 846 patients with RA was recruited, of which 589 patients of working age at disease onset constituted the study population. Information on the socio-demographic, clinical, working and financial conditions of the patients was collected. Logistic regression analyses were used to identify factors associated with work capacity impairment. RESULTS: The rate of work capacity impairment was 48.0% in RA patients with a mean disease duration of 60 months (interquartile range 14-134 months), including 11.7% leaving the labour force early, 33.6% working reduced hours and 2.7% changing job. Multivariable logistic regression analysis showed that reduced working hours was significantly related to current smoking [odds ratio (OR) 2.07 (95% CI 1.08, 3.97)], no insurance [OR 1.94 (95% CI 1.20, 3.12)], in manual labour [OR 2.66 (95% CI 1.68, 4.20)] and higher HAQ score [OR 2.22 (95% CI 1.36, 3.60)]. There was an association of current smoking [OR 3.75 (95% CI 1.54, 9.15)], in manual labour [OR 2.33 (95% CI 1.17, 4.64)], longer disease duration [OR 1.01 (95% CI 1.00, 1.01)] and lower BMI [OR 0.90 (95% CI 0.82, 0.99)] with leaving the labour force early. CONCLUSION: There is a substantial impact of RA on the work capacity of patients in China. Social-demographic, disease- and work-related factors are all associated with work capacity impairment.