Janine M Duke1, Suzanne Rea2, James H Boyd3, Sean M Randall3, Fiona M Wood2. 1. Burn Injury Research Unit, School of Surgery, University of Western Australia, Perth, Australia; janine.duke@uwa.edu.au. 2. Burn Injury Research Unit, School of Surgery, University of Western Australia, Perth, Australia; Burns Service of Western Australia, Royal Perth Hospital and Princess Margaret Hospital, Perth, Australia; and. 3. Population Health Research Network Centre for Data Linkage, Curtin University, Perth, Australia.
Abstract
OBJECTIVE: To assess the impact of burn injury sustained during childhood on long-term mortality and to quantify any increased risk of death attributable to burn injury. METHODS: A population-based cohort study of children younger than 15 years hospitalized for burn injury in Western Australia (1980-2012) and a matched noninjured comparison group. Deidentified extraction of linked hospital morbidity and death records for the period 1980-2012 were provided by the Western Australian Data Linkage System. An inception cohort (1980-2012) of burn cases younger than 15 years of age when hospitalized for a first burn injury (n = 10,426) and a frequency matched noninjured comparison cohort (n = 40,818) were identified. Survival analysis was conducted by using the Kaplan-Meier method and Cox proportional hazards regression. Mortality rate ratios and attributable risk percent adjusted for sociodemographic and preexisting heath factors were generated. RESULTS: The median follow-up time for the pediatric burn cohort was 18.1 years after discharge. The adjusted all-cause mortality rate ratios for burn injury was 1.6 (95% confidence interval: 1.3-2.0); children with burn injury had a 1.6 times greater rate of mortality than those with no injury. The index burn injury was estimated to account for 38% (attributable risk percent) of all recorded deaths in the burn injury cohort during the study period. CONCLUSIONS: Burn injury sustained by children is associated with an increased risk of long-term all-cause mortality. Estimates of the total mortality burden based on in-hospital deaths alone underestimates the true burden from burn injury.
OBJECTIVE: To assess the impact of burn injury sustained during childhood on long-term mortality and to quantify any increased risk of death attributable to burn injury. METHODS: A population-based cohort study of children younger than 15 years hospitalized for burn injury in Western Australia (1980-2012) and a matched noninjured comparison group. Deidentified extraction of linked hospital morbidity and death records for the period 1980-2012 were provided by the Western Australian Data Linkage System. An inception cohort (1980-2012) of burn cases younger than 15 years of age when hospitalized for a first burn injury (n = 10,426) and a frequency matched noninjured comparison cohort (n = 40,818) were identified. Survival analysis was conducted by using the Kaplan-Meier method and Cox proportional hazards regression. Mortality rate ratios and attributable risk percent adjusted for sociodemographic and preexisting heath factors were generated. RESULTS: The median follow-up time for the pediatric burn cohort was 18.1 years after discharge. The adjusted all-cause mortality rate ratios for burn injury was 1.6 (95% confidence interval: 1.3-2.0); children with burn injury had a 1.6 times greater rate of mortality than those with no injury. The index burn injury was estimated to account for 38% (attributable risk percent) of all recorded deaths in the burn injury cohort during the study period. CONCLUSIONS:Burn injury sustained by children is associated with an increased risk of long-term all-cause mortality. Estimates of the total mortality burden based on in-hospital deaths alone underestimates the true burden from burn injury.
Authors: Eric Rivas; David N Herndon; Martha L Chapa; Janos Cambiaso-Daniel; Victoria G Rontoyanni; Ileana L Gutierrez; Kevin Sanchez; Shauna Glover; Oscar E Suman Journal: Burns Date: 2018-02-09 Impact factor: 2.744
Authors: Lucy W Barrett; Vanessa S Fear; Bree Foley; Katherine Audsley; Samantha Barnes; Hannah Newnes; Alison McDonnell; Fiona M Wood; Mark W Fear; Jason Waithman Journal: Burns Trauma Date: 2022-04-29
Authors: Christian Tapking; Daniel Popp; David N Herndon; Andrew M Armenta; Ludwik K Branski; Andrew J Murton; Oscar E Suman Journal: J Burn Care Res Date: 2019-01-01 Impact factor: 1.845