Literature DB >> 2580205

Amphetamine stimulation of glutaminase is blocked by neuroleptics.

A D Sherman, J Mott.   

Abstract

The ability of several classes of neuroleptics to inhibit the activity of phosphate-activated glutaminase was studied in several brain regions. These agents decreased glutaminase activity only in the amygdala. Amphetamine elevated glutaminase activity in this region. This stimulation was not blocked by (-) butaclamol, but was blocked by (+) butaclamol, haloperidol, chlorpromazine or clozapine.

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Year:  1985        PMID： 2580205     DOI： 10.1016/0024-3205(85)90233-4

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  5 in total

1.  Psychostimulant drug effects on glutamate, Glx, and creatine in the anterior cingulate cortex and subjective response in healthy humans.

Authors:  Tara L White; Mollie A Monnig; Edward G Walsh; Adam Z Nitenson; Ashley D Harris; Ronald A Cohen; Eric C Porges; Adam J Woods; Damon G Lamb; Chelsea A Boyd; Sinda Fekir
Journal:  Neuropsychopharmacology       Date:  2018-03-06       Impact factor: 7.853

2.  Amphetamine increases extracellular concentrations of glutamate in the prefrontal cortex of the awake rat: a microdialysis study.

Authors:  A Del Arco; R Martínez; F Mora
Journal:  Neurochem Res       Date:  1998-09       Impact factor: 3.996

3.  How high-resolution basal-state functional imaging can guide the development of new pharmacotherapies for schizophrenia.

Authors:  Inna Gaisler-Salomon; Scott A Schobel; Scott A Small; Stephen Rayport
Journal:  Schizophr Bull       Date:  2009-10-14       Impact factor: 9.306

4.  Dopamine D1 receptor activation drives plasticity in the songbird auditory pallium.

Authors:  Matheus Macedo-Lima; Hannah M Boyd; Luke Remage-Healey
Journal:  J Neurosci       Date:  2021-06-01       Impact factor: 6.167

5.  The neurobiology of wellness: 1H-MRS correlates of agency, flexibility and neuroaffective reserves in healthy young adults.

Authors:  Tara L White; Meghan A Gonsalves; Ronald A Cohen; Ashley D Harris; Mollie A Monnig; Edward G Walsh; Adam Z Nitenson; Eric C Porges; Damon G Lamb; Adam J Woods; Cara B Borja
Journal:  Neuroimage       Date:  2020-10-27       Impact factor: 6.556
  5 in total

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