| Literature DB >> 25801779 |
Solène Le Gal1, Laurence Pougnet2, Céline Damiani3, Emilie Fréalle4, Paul Guéguen5, Michèle Virmaux6, Séverine Ansart7, Sylvain Jaffuel8, Francis Couturaud9, Aurélien Delluc9, Jean-Marie Tonnelier10, Philippe Castellant11, Yann Le Meur12, Gaétan Le Floch6, Anne Totet3, Jean Menotti13, Gilles Nevez14.
Abstract
In this study, Pneumocystis jirovecii was detected and characterized in the air surrounding patients with Pneumocystis pulmonary colonization. Air samples were collected in the rooms of 10 colonized patients using Coriolis® μ air sampler at 1m and 5m from the patient's head. P. jirovecii DNA was amplified and genotyped in pulmonary and air samples at the mitochondrial large subunit ribosomal RNA gene. P. jirovecii DNA was detected in 5 of the 10 air samples collected at 1m and in 5 of the 10 other air samples collected at 5m. P. jirovecii genotyping was successful in 4 pairs or triplets of air and pulmonary samples. Full genotype matches were observed in 3 of the 4 pairs or triplets of air and pulmonary samples. These results provide original data supporting P. jirovecii exhalation from colonized patients and emphasize the risk of P. jirovecii nosocomial transmission from this patient population.Entities:
Keywords: Airborne transmission; Colonization; Exhalation; Pneumocystis jirovecii
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Year: 2015 PMID： 25801779 DOI： 10.1016/j.diagmicrobio.2015.01.004
Source DB: PubMed Journal: Diagn Microbiol Infect Dis ISSN： 0732-8893 Impact factor: 2.803