Literature DB >> 25801541

Emergency endotracheal intubation-related adverse events in bronchial asthma exacerbation: can anesthesiologists attenuate the risk?

Yuko Ono1,2, Hiroaki Kikuchi3, Katsuhiko Hashimoto3, Tetsu Sasaki3, Jyunya Ishii3, Choichiro Tase4, Kazuaki Shinohara3.   

Abstract

PURPOSE: Airway management in severe bronchial asthma exacerbation (BAE) carries very high risk and should be performed by experienced providers. However, no objective data are available on the association between the laryngoscopist's specialty and endotracheal intubation (ETI)-related adverse events in patients with severe bronchial asthma. In this paper, we compare emergency ETI-related adverse events in patients with severe BAE between anesthesiologists and other specialists.
METHODS: This historical cohort study was conducted at a Japanese teaching hospital. We analyzed all BAE patients who underwent ETI in our emergency department from January 2002 to January 2014. Primary exposure was the specialty of the first laryngoscopist (anesthesiologist vs. other specialist). The primary outcome measure was the occurrence of an ETI-related adverse event, including severe bronchospasm after laryngoscopy, hypoxemia, regurgitation, unrecognized esophageal intubation, and ventricular tachycardia.
RESULTS: Of 39 patients, 21 (53.8 %) were intubated by an anesthesiologist and 18 (46.2 %) by other specialists. Crude analysis revealed that ETI performed by an anesthesiologist was significantly associated with attenuated risk of ETI-related adverse events [odds ratio (OR) 0.090, 95 % confidence interval (CI) 0.020-0.41, p = 0.001]. The benefit of attenuated risk remained significant after adjusting for potential confounders, including Glasgow Coma Score, age, and use of a neuromuscular blocking agent (OR 0.058, 95 % CI 0.010-0.35, p = 0.0020).
CONCLUSIONS: Anesthesiologist as first exposure was independently associated with attenuated risk of ETI-related adverse events in patients with severe BAE. The skill and knowledge of anesthesiologists should be applied to high-risk airway management whenever possible.

Entities:  

Keywords:  Airway management; Fatal asthma; Mechanical ventilation; Status asthmaticus

Mesh:

Year:  2015        PMID: 25801541     DOI: 10.1007/s00540-015-2003-2

Source DB:  PubMed          Journal:  J Anesth        ISSN: 0913-8668            Impact factor:   2.078


  30 in total

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4.  Emergency department use of ketamine in pediatric status asthmaticus.

Authors:  T M Petrillo; J D Fortenberry; J F Linzer; H K Simon
Journal:  J Asthma       Date:  2001-12       Impact factor: 2.515

5.  Comparative effects of thiopentone and propofol on respiratory resistance after tracheal intubation.

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6.  Emergency airway management: a multi-center report of 8937 emergency department intubations.

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7.  Costs of asthma in the United States: 2002-2007.

Authors:  Sarah Beth L Barnett; Tursynbek A Nurmagambetov
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8.  Mechanisms of bronchoprotection by anesthetic induction agents: propofol versus ketamine.

Authors:  R H Brown; E M Wagner
Journal:  Anesthesiology       Date:  1999-03       Impact factor: 7.892

9.  Endotracheal intubation and mechanical ventilation in severe asthma.

Authors:  J L Zimmerman; R P Dellinger; A N Shah; R W Taylor
Journal:  Crit Care Med       Date:  1993-11       Impact factor: 7.598

10.  Rapid-sequence intubation at an emergency medicine residency: success rate and adverse events during a two-year period.

Authors:  V S Tayal; R W Riggs; J A Marx; C A Tomaszewski; R E Schneider
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  4 in total

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Journal:  Ann Intensive Care       Date:  2019-10-10       Impact factor: 6.925

3.  Association between off-hour presentation and endotracheal-intubation-related adverse events in trauma patients with a predicted difficult airway: A historical cohort study at a community emergency department in Japan.

Authors:  Yuko Ono; Takuya Sugiyama; Yasuyuki Chida; Tetsuya Sato; Hiroaki Kikuchi; Daiji Suzuki; Masakazu Ikeda; Koichi Tanigawa; Kazuaki Shinohara
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4.  Human and equipment resources for difficult airway management, airway education programs, and capnometry use in Japanese emergency departments: a nationwide cross-sectional study.

Authors:  Yuko Ono; Koichi Tanigawa; Kazuaki Shinohara; Tetsuhiro Yano; Kotaro Sorimachi; Ryota Inokuchi; Jiro Shimada
Journal:  Int J Emerg Med       Date:  2017-09-13
  4 in total

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