Hyun-Dong Cho1, Ju-Hye Lee2, Ji-Hye Jeong1, Jae-Yong Kim3, Sung-Tae Yee4, Seok-Kyu Park1, Mi-Kyung Lee1, Kwon-Il Seo1. 1. Department of Food and Nutrition, Sunchon National University, Suncheon, 540-950, Republic of Korea. 2. Research Institute of Basic Science, Sunchon National University, Suncheon, 540-950, Republic of Korea. 3. Jeonnam Institute of natural resources research, Jangheung, 529-851, Republic of Korea. 4. Department of Pharmacy, Sunchon National University, Suncheon, 540-950, Republic of Korea.
Abstract
BACKGROUND: Salicornia herbacea L. is a halophyte that grows in salt marshes and contains significant amounts of salts and minerals. Because it is known as a folk medication to treat diseases, various processed products such as powder, globular type of powder, laver and extract have been developed. However, it is difficult to process as a drink because of its high salinity. In the present study, glasswort vinegar (GV) containing high amounts of organic acids and minerals was developed via two-step fermentation with unpolished rice substrates and investigated its antioxidant and anti-fatigue activities. RESULTS: GV showed various free radical scavenging effects, reducing power, oxidized-LDL inhibition and superoxide dismutase-like activities. Compared with the control group (orally administered 7 g kg(-1) distilled water), the GV supplementation group showed increased running endurance and had higher glycogen accumulation in liver and muscles of rats exhausted by exercise. Furthermore, the GV-administered group demonstrated significantly elevated lactate and ATP metabolism, promoting enzyme activities such as muscle creatine kinase and lactate dehydrogenase, whereas serum fatigue biomarkers such as ammonia, lactate and inorganic acid were markedly decreased. CONCLUSION: These results indicate that GV can be used as a functional food for the development of a dietary beverage to alleviate fatigue.
BACKGROUND:Salicornia herbacea L. is a halophyte that grows in salt marshes and contains significant amounts of salts and minerals. Because it is known as a folk medication to treat diseases, various processed products such as powder, globular type of powder, laver and extract have been developed. However, it is difficult to process as a drink because of its high salinity. In the present study, glasswort vinegar (GV) containing high amounts of organic acids and minerals was developed via two-step fermentation with unpolished rice substrates and investigated its antioxidant and anti-fatigue activities. RESULTS:GV showed various free radical scavenging effects, reducing power, oxidized-LDL inhibition and superoxide dismutase-like activities. Compared with the control group (orally administered 7 g kg(-1) distilled water), the GV supplementation group showed increased running endurance and had higher glycogen accumulation in liver and muscles of rats exhausted by exercise. Furthermore, the GV-administered group demonstrated significantly elevated lactate and ATP metabolism, promoting enzyme activities such as muscle creatine kinase and lactate dehydrogenase, whereas serum fatigue biomarkers such as ammonia, lactate and inorganic acid were markedly decreased. CONCLUSION: These results indicate that GV can be used as a functional food for the development of a dietary beverage to alleviate fatigue.
Authors: Ali Alhoshani; Fahad O Alatawi; Fawaz E Al-Anazi; Ibraheem M Attafi; Asad Zeidan; Abdelali Agouni; Heba M El Gamal; Licia S Shamoon; Sarah Khalaf; Hesham M Korashy Journal: Onco Targets Ther Date: 2020-12-31 Impact factor: 4.147