Literature DB >> 25800897

Epigenetic changes in BRCA1-mutated familial breast cancer.

Bradley Downs1, San Ming Wang2.   

Abstract

Familial breast cancer occurs in about 10% of breast cancer cases. Germline mutation in BRCA1 is the most penetrant predisposition for the disease. Mutated BRCA1 leads to disease by causing genome instability via multiple mechanisms including epigenetic changes. This review summarizes recent progress in studying the correlation between BRCA1 predisposition and epigenetic alterations in BRCA1-type familial breast cancer.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  BRCA1; autosomal dominant; epigenetic alteration; familial breast cancer; germline mutation

Mesh：

Substances：

Year:  2015        PMID： 25800897      PMCID： PMC4466075          DOI： 10.1016/j.cancergen.2015.02.001

Source DB:  PubMed          Journal:  Cancer Genet


  41 in total

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Journal:  Genomics       Date:  2000-05-01       Impact factor: 5.736

2.  BRCA1 interacts with components of the histone deacetylase complex.

Authors:  R I Yarden; L C Brody
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

Review 3.  Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: recommendation statement.

Authors: 
Journal:  Ann Intern Med       Date:  2005-09-06       Impact factor: 25.391

4.  Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases.

Authors:  M Okano; S Xie; E Li
Journal:  Nat Genet       Date:  1998-07       Impact factor: 38.330

5.  Two decades after BRCA: setting paradigms in personalized cancer care and prevention.

Authors:  Fergus J Couch; Katherine L Nathanson; Kenneth Offit
Journal:  Science       Date:  2014-03-28       Impact factor: 47.728

6.  CpG island methylator phenotype in colorectal cancer.

Authors:  M Toyota; N Ahuja; M Ohe-Toyota; J G Herman; S B Baylin; J P Issa
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

7.  Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer.

Authors:  K P M Suijkerbuijk; M J Fackler; S Sukumar; C H van Gils; T van Laar; E van der Wall; M Vooijs; P J van Diest
Journal:  Ann Oncol       Date:  2008-07-22       Impact factor: 32.976

8.  CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.

Authors:  Shauna N Vasilatos; Gloria Broadwater; William T Barry; Joseph C Baker; Siya Lem; Eric C Dietze; Gregory R Bean; Andrew D Bryson; Patrick G Pilie; Vanessa Goldenberg; David Skaar; Carolyn Paisie; Alejandro Torres-Hernandez; Tracey L Grant; Lee G Wilke; Catherine Ibarra-Drendall; Julie H Ostrander; Nicholas C D'Amato; Carola Zalles; Randy Jirtle; Valerie M Weaver; Victoria L Seewaldt
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2009-03-03       Impact factor: 4.254

9.  A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.

Authors:  A Yoshimura; T Ohkubo; T Kiguchi; N A Jenkins; D J Gilbert; N G Copeland; T Hara; A Miyajima
Journal:  EMBO J       Date:  1995-06-15       Impact factor: 11.598

10.  Alu and LINE-1 hypomethylation is associated with HER2 enriched subtype of breast cancer.

Authors:  So Yeon Park; An Na Seo; Hae Yoen Jung; Jae Moon Gwak; Namhee Jung; Nam-Yun Cho; Gyeong Hoon Kang
Journal:  PLoS One       Date:  2014-06-27       Impact factor: 3.240
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  3 in total

1.  Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition.

Authors:  Hemant Gupta; Khyati Chandratre; Siddharth Sinha; Teng Huang; Xiaobing Wu; Jian Cui; Michael Q Zhang; San Ming Wang
Journal:  BMC Genomics       Date:  2020-11-30       Impact factor: 3.969

2.  BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays.

Authors:  Abeer M Mahmoud; Virgilia Macias; Umaima Al-Alem; Ryan J Deaton; Andre Kadjaksy-Balla; Peter H Gann; Garth H Rauscher
Journal:  PLoS One       Date:  2017-09-01       Impact factor: 3.240

Review 3.  Epigenetics in Inflammatory Breast Cancer: Biological Features and Therapeutic Perspectives.

Authors:  Flavia Lima Costa Faldoni; Cláudia Aparecida Rainho; Silvia Regina Rogatto
Journal:  Cells       Date:  2020-05-08       Impact factor: 6.600
  3 in total

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