Roberto Luigi Cazzato1, Jean Palussière2, Xavier Buy3, Vincenzo Denaro4, Daniele Santini5, Giuseppe Tonini6, Rosario Francesco Grasso7, Bruno Beomonte Zobel8, Dario Poretti9, Vittorio Pedicini10, Luca Balzarini11, Ezio Lanza12. 1. Department of Radiology, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 200, 00128, Rome, Italy. r.cazzato@unicampus.it. 2. Department of Radiology, Institut Bergonié, 229 Cours de l'Argonne, 33000, Bordeaux, France. j.palussiere@bordeaux.unicancer.fr. 3. Department of Radiology, Institut Bergonié, 229 Cours de l'Argonne, 33000, Bordeaux, France. x.buy@bordeaux.unicancer.fr. 4. Department of Medical Oncology, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 200, 00128, Rome, Italy. denaro@unicampus.it. 5. Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 200, 00128, Rome, Italy. d.santini@unicampus.it. 6. Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 200, 00128, Rome, Italy. g.tonini@unicampus.it. 7. Department of Radiology, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 200, 00128, Rome, Italy. r.grasso@unicampus.it. 8. Department of Radiology, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 200, 00128, Rome, Italy. b.zobel@unicampus.it. 9. Department of Radiology, Humanitas Research Hospital, 20089, Rozzano, Milan, Italy. dario.poretti@humanitas.it. 10. Department of Radiology, Humanitas Research Hospital, 20089, Rozzano, Milan, Italy. vittorio.pedicini@humanitas.it. 11. Department of Radiology, Humanitas Research Hospital, 20089, Rozzano, Milan, Italy. luca.balzarini@humanitas.it. 12. Department of Radiology, Humanitas Research Hospital, 20089, Rozzano, Milan, Italy. ezio.lanza@humanitas.it.
Abstract
PURPOSE: Percutaneous cementoplasty (PC) is rarely applied to long bone tumours, since cement is not considered to be sufficiently resistant to torsional forces. We reviewed the literature to understand the effects of percutaneous long bone cementoplasty (PLBC) in terms of analgesia, limb function and complications. MATERIALS AND METHODS: This study followed the Cochrane's guidelines for systematic reviews of interventions. Inclusion criteria were (1) prospective/retrospective studies concerning PC; (2) cohort including at least ten patients; (3) at least one patient in the cohort undergoing PLBC; (5) published in English; (6) results not published by the same author more than once. RESULTS: One thousand five hundred and ninety-eight articles were screened and 13 matched the inclusion criteria covering 196 PLBC patients. Pain improvement was high in 68.2% patients (σ = 0.2) and mild in 27.4% (σ = 0.2). Functional improvement was high in 71.9% patients (σ = 0.1) and mild in 6% (σ = 0.1). Use of PLBC correlated with pain reduction (P < 0.001). Secondary fractures occurred in 16 cases (8%, σ = 2.5); other complications in 2% cases. Percutaneous stabilisation (PS) was coupled with PLBC in 17% of cases without any subsequent fracture. PS was not associated with absence of secondary fracture (P = 0.08). CONCLUSION: PLBC is safe, offering good pain relief and recovery of impaired limb function. Secondary fractures are uncommon and PS may reduce their occurrence. However, no evidence is currently available to support PS plus PLBC as compared to PLBC alone.
PURPOSE: Percutaneous cementoplasty (PC) is rarely applied to long bone tumours, since cement is not considered to be sufficiently resistant to torsional forces. We reviewed the literature to understand the effects of percutaneous long bone cementoplasty (PLBC) in terms of analgesia, limb function and complications. MATERIALS AND METHODS: This study followed the Cochrane's guidelines for systematic reviews of interventions. Inclusion criteria were (1) prospective/retrospective studies concerning PC; (2) cohort including at least ten patients; (3) at least one patient in the cohort undergoing PLBC; (5) published in English; (6) results not published by the same author more than once. RESULTS: One thousand five hundred and ninety-eight articles were screened and 13 matched the inclusion criteria covering 196 PLBCpatients. Pain improvement was high in 68.2% patients (σ = 0.2) and mild in 27.4% (σ = 0.2). Functional improvement was high in 71.9% patients (σ = 0.1) and mild in 6% (σ = 0.1). Use of PLBC correlated with pain reduction (P < 0.001). Secondary fractures occurred in 16 cases (8%, σ = 2.5); other complications in 2% cases. Percutaneous stabilisation (PS) was coupled with PLBC in 17% of cases without any subsequent fracture. PS was not associated with absence of secondary fracture (P = 0.08). CONCLUSION:PLBC is safe, offering good pain relief and recovery of impaired limb function. Secondary fractures are uncommon and PS may reduce their occurrence. However, no evidence is currently available to support PS plus PLBC as compared to PLBC alone.
Entities:
Keywords:
Long bone; Pathological fracture; Percutaneous cementoplasty
Authors: Roberto Luigi Cazzato; Julien Garnon; Nitin Ramamurthy; Guillaume Koch; Georgia Tsoumakidou; Jean Caudrelier; Francesco Arrigoni; Luigi Zugaro; Antonio Barile; Carlo Masciocchi; Afshin Gangi Journal: Med Oncol Date: 2016-11-11 Impact factor: 3.064
Authors: Antonio Barile; Francesco Arrigoni; Luigi Zugaro; Marcello Zappia; Roberto Luigi Cazzato; Julien Garnon; Nitin Ramamurthy; Luca Brunese; Afshin Gangi; Carlo Masciocchi Journal: Med Oncol Date: 2017-02-24 Impact factor: 3.064