Literature DB >> 25799262

Protein stabilization by an amphiphilic short monodisperse oligo(ethylene glycol).

Nabanita Sadhukhan1, Takahiro Muraoka, Mihoko Ui, Satoru Nagatoishi, Kouhei Tsumoto, Kazushi Kinbara.   

Abstract

A short, monodisperse additive (octa(ethylene glycol) monophenyl ether) functions to suppress aggregation of thermally and chemically denatured lysozyme. Control studies with shorter and non-amphiphilic derivatives revealed that the amphiphilic structure is essential, and octa(ethylene glycol) is nearly the minimum chain length for amphiphilic poly(ethylene glycol)s to stabilize proteins.

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Year:  2015        PMID: 25799262     DOI: 10.1039/c4cc10301g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Soft Nanotubes Derivatized with Short PEG Chains for Thermally Controllable Extraction and Separation of Peptides.

Authors:  Naohiro Kameta; Wuxiao Ding; Jiuchao Dong
Journal:  ACS Omega       Date:  2017-09-26
  1 in total

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