Literature DB >> 2579847

A structural and dynamic molecular model for the sodium channel of Electrophorus electricus.

E M Kosower.   

Abstract

Chemical logic and single group rotation (SGR) theory are applied to the primary structure determined by Noda et al. [(1984) Nature 312, 121-127] to construct a molecular model of the sodium channel of Electrophorus electricus. Both structural and dynamic aspects of the channel are accounted for, including gating current, sensitivity to changes in membrane potential, channel opening, a binding site for sodium, selectivity for sodium over potassium, capacity for rapid sodium flow, sensitivity to batrachotoxin (or other toxins) and inactivation.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2579847     DOI： 10.1016/0014-5793(85)80306-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  15 in total

1.  Involvement of different S4 parts in the voltage dependency of Na channel gating.

Authors:  Z Kra-Oz; G Spira; Y Palti; H Meiri
Journal:  J Membr Biol       Date:  1992-08       Impact factor: 1.843

2.  Depolarization exposes the voltage sensor of the sodium channels to the extracellular region.

Authors:  M Sammar; G Spira; H Meiri
Journal:  J Membr Biol       Date:  1992-01       Impact factor: 1.843

3.  The quantal gating charge of sodium channel inactivation.

Authors:  N G Greeff; I C Forster
Journal:  Eur Biophys J       Date:  1991       Impact factor: 1.733

4.  Long-range interactions, voltage sensitivity, and ion conduction in S4 segments of excitable channels.

Authors:  H R Leuchtag
Journal:  Biophys J       Date:  1994-01       Impact factor: 4.033

5.  3₁₀-helix conformation facilitates the transition of a voltage sensor S4 segment toward the down state.

Authors:  Christine S Schwaiger; Pär Bjelkmar; Berk Hess; Erik Lindahl
Journal:  Biophys J       Date:  2011-03-16       Impact factor: 4.033

Review 6.  Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions.

Authors:  J Alfredo Freites; Douglas J Tobias
Journal:  J Membr Biol       Date:  2015-05-14       Impact factor: 1.843

7.  Grayanotoxin opens Na channels from inside the squid axonal membrane.

Authors:  I Seyama; K Yamada; R Kato; T Masutani; M Hamada
Journal:  Biophys J       Date:  1988-02       Impact factor: 4.033

8.  Channel protein engineering: synthetic 22-mer peptide from the primary structure of the voltage-sensitive sodium channel forms ionic channels in lipid bilayers.

Authors:  S Oiki; W Danho; M Montal
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

Review 9.  Reconstitution of channel proteins from excitable cells in planar lipid bilayer membranes.

Authors:  M Montal
Journal:  J Membr Biol       Date:  1987       Impact factor: 1.843

10.  Mapping a region associated with Na channel inactivation using antibodies to a synthetic peptide corresponding to a part of the channel.

Authors:  H Meiri; G Spira; M Sammar; M Namir; A Schwartz; A Komoriya; E M Kosower; Y Palti
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.