Literature DB >> 25798253

Advances in the application of nanotechnology in the diagnosis and treatment of gastrointestinal tumors.

B O Sun1, Yantian Fang1, Zhengyang Li1, Zongyou Chen1, Jianbin Xiang1.   

Abstract

Nanotechnology has broad application prospects in the diagnosis and treatment of cancer. Integrating chemistry, engineering, biology and medicine, nanotechnology is a multidisciplinary research field. Nanoscale imaging technology significantly improves the precision and accuracy of tumor diagnosis. Nanocarriers are able to significantly improve the accuracy of dose and targeted drug delivery and reduce the toxic side effects. This review focuses on the emerging roles of these innovative technologies in gastrointestinal cancer diagnostics and therapeutics. Although several problems and barriers are hampering the development of nanodevices, the potential for nanotechnologies to function as multimodal nanotheranostic agents will likely pave the way for the fight against gastrointestinal cancer.

Entities:  

Keywords:  colon tumor; gastric tumor; gastrointestinal tumors; nanotechnology

Year:  2014        PMID: 25798253      PMCID: PMC4360882          DOI: 10.3892/mco.2014.470

Source DB:  PubMed          Journal:  Mol Clin Oncol        ISSN: 2049-9450


  76 in total

1.  Quantum-dots based simultaneous detection of multiple biomarkers of tumor stromal features to predict clinical outcomes in gastric cancer.

Authors:  Chun-Wei Peng; Qian Tian; Gui-Fang Yang; Min Fang; Zhi-Ling Zhang; Jun Peng; Yan Li; Dai-Wen Pang
Journal:  Biomaterials       Date:  2012-05-16       Impact factor: 12.479

2.  Cantilever-based optical deflection assay for discrimination of DNA single-nucleotide mismatches.

Authors:  K M Hansen; H F Ji; G Wu; R Datar; R Cote; A Majumdar; T Thundat
Journal:  Anal Chem       Date:  2001-04-01       Impact factor: 6.986

Review 3.  Emerging implications of nanotechnology on cancer diagnostics and therapeutics.

Authors:  Alex G Cuenca; Huabei Jiang; Steven N Hochwald; Matthew Delano; William G Cance; Stephen R Grobmyer
Journal:  Cancer       Date:  2006-08-01       Impact factor: 6.860

4.  Biorecognition layer engineering: overcoming screening limitations of nanowire-based FET devices.

Authors:  Roey Elnathan; Moria Kwiat; Alexander Pevzner; Yoni Engel; Larisa Burstein; Artium Khatchtourints; Amir Lichtenstein; Raisa Kantaev; Fernando Patolsky
Journal:  Nano Lett       Date:  2012-09-10       Impact factor: 11.189

5.  Microfluidic bead-based multienzyme-nanoparticle amplification for detection of circulating tumor cells in the blood using quantum dots labels.

Authors:  He Zhang; Xin Fu; Jiayi Hu; Zhenjun Zhu
Journal:  Anal Chim Acta       Date:  2013-04-06       Impact factor: 6.558

6.  3D MR angiography of intratumoral vasculature using a novel macromolecular MR contrast agent.

Authors:  H Kobayashi; N Sato; S Kawamoto; T Saga; A Hiraga; T Ishimori; J Konishi; K Togashi; M W Brechbiel
Journal:  Magn Reson Med       Date:  2001-09       Impact factor: 4.668

7.  Real time in vivo non-invasive optical imaging using near-infrared fluorescent quantum dots.

Authors:  Nicole Y Morgan; Sean English; Wei Chen; Victor Chernomordik; Angelo Russo; Paul D Smith; Amir Gandjbakhche
Journal:  Acad Radiol       Date:  2005-03       Impact factor: 3.173

8.  Sentinel lymph node mapping of the gastrointestinal tract by using invisible light.

Authors:  Edward G Soltesz; Sungjee Kim; Sang-Wook Kim; Rita G Laurence; Alec M De Grand; Cherie P Parungo; Lawrence H Cohn; Moungi G Bawendi; John V Frangioni
Journal:  Ann Surg Oncol       Date:  2006-01-31       Impact factor: 5.344

9.  Biodegradable cationic nanoparticles loaded with an anticancer drug for deep penetration of heterogeneous tumours.

Authors:  Hyeona Yim; Sin-jung Park; You Han Bae; Kun Na
Journal:  Biomaterials       Date:  2013-07-18       Impact factor: 12.479

10.  Semiconductor quantum dots as fluorescent probes for in vitro and in vivo bio-molecular and cellular imaging.

Authors:  Sarwat B Rizvi; Shirin Ghaderi; Mo Keshtgar; Alexander M Seifalian
Journal:  Nano Rev       Date:  2010-08-16
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  1 in total

Review 1.  In vivo gene delivery mediated by non-viral vectors for cancer therapy.

Authors:  Reza Mohammadinejad; Ali Dehshahri; Vijay Sagar Madamsetty; Masoumeh Zahmatkeshan; Shima Tavakol; Pooyan Makvandi; Danial Khorsandi; Abbas Pardakhty; Milad Ashrafizadeh; Elham Ghasemipour Afshar; Ali Zarrabi
Journal:  J Control Release       Date:  2020-07-04       Impact factor: 9.776

  1 in total

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