| Literature DB >> 25797159 |
Hong X Ding1, Carolyn A Leverett2, Robert E Kyne3, Kevin K-C Liu4, Sarah J Fink5, Andrew C Flick6, Christopher J O'Donnell7.
Abstract
New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition and also serve as leads for designing future new drugs. This annual review covers the synthesis of twenty-four NCEs that were approved for the first time in 2013 and two 2012 drugs which were not covered during the previous edition of this review.Keywords: Medicine; New chemical entities; New drug molecules; Synthesis; Therapeutic agents
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Year: 2015 PMID： 25797159 DOI： 10.1016/j.bmc.2015.02.056
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641