Literature DB >> 2579670

Isoquinoline is a possible anti-psoriatic agent in coal tar.

M I Foreman, M Taylor, C Clark, H Devitt, G Hanlon, I Kelly, G Lukowiecki.   

Abstract

Isoquinoline has been identified as a component of coal tar which causes interfollicular regions of parakeratotic stratum corneum in mouse tail epidermis to become orthokeratotic, with concomitant production of a granular layer. In this respect it behaves similarly to coal tar itself, and isoquinoline may contribute to the anti-psoriatic activity of coal tar.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 2579670     DOI: 10.1111/j.1365-2133.1985.tb04860.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  1 in total

1.  Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.

Authors:  Sumit Punj; Prasad Kopparapu; Hyo Sang Jang; Jessica L Phillips; Jamie Pennington; Diana Rohlman; Edmond O'Donnell; Patrick L Iversen; Siva Kumar Kolluri; Nancy I Kerkvliet
Journal:  PLoS One       Date:  2014-02-19       Impact factor: 3.240

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.