| Literature DB >> 25796532 |
Monika Fraczek1, Maciej Kurpisz2.
Abstract
Cell integration between the immune and reproductive systems is the basis for normal male reproductive physiology. Cytokines are a part of the autocrine/paracrine network operating in the male reproductive tract. At the same time, immunological reactions occurring via cytokines appear to be both beneficial and/or risk factors for male fertility. As the cytokines are produced by a whole spectrum of cells in all compartments of the male genital tract, they can also be involved in a variety of andrological disorders. The monitoring of cytokines and other immune factors in seminal plasma may offer a chance to better understand the mechanisms leading to sub-/infertility. In this review, we present insights into cytokine interplay in some of the pathological conditions associated with male reproduction.Entities:
Keywords: Cryptorchidism; Cytokines; Oxidative stress; Semen inflammation; Varicocele
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Year: 2015 PMID： 25796532 DOI： 10.1016/j.jri.2015.02.001
Source DB: PubMed Journal: J Reprod Immunol ISSN： 0165-0378 Impact factor: 4.054