Camille Daraï1, Olivier Deboute2, Chrysoula Zacharopoulou3, Enora Laas3, Geoffroy Canlorbe3, Jéremie Belghiti3, Sonia Zilberman3, Marcos Ballester4, Emile Daraï5. 1. Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France; Institut Privé d'Enseignement Ostéopathique (IPEO), 5/13 rue Auger, Pantin, France. 2. Institut Privé d'Enseignement Ostéopathique (IPEO), 5/13 rue Auger, Pantin, France. 3. Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France. 4. Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France; UMRS938, Université Pierre et Marie Curie, Paris 6, France. 5. Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France; UMRS938, Université Pierre et Marie Curie, Paris 6, France. Electronic address: emile.darai@tnn.aphp.fr.
Abstract
OBJECTIVE: A prospective pilot study to evaluate the potential role of osteopathic manipulative therapy (OMT) on quality of life (QOL) of patients with Deep Infiltrating Endometriosis (DIE) and colorectal involvement. STUDY DESIGN: Twenty patients with DIE and colorectal infiltration completed the SF-36 QOL questionnaire before and after undergoing OMT. RESULTS: The median age (range) of the patients was 30.4 years (22-39). Thirty-five percent of the patients had undergone previous surgery for endometriosis and 70% were on medical treatment. Fifteen of the 20 patients (75%) completed the protocol. There was no difference in the epidemiological characteristics or in the pre-OMT Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36 questionnaire between patients who completed the protocol or not. After a mean period of 24 days (15-53), a significant improvement in PCS (p=0.03) and MCS (p=0.0009) compared to pre-OMT values was observed giving a success rate of 80% and 60% in intention-to-treat, respectively. CONCLUSION: Our results support that OMT can improve QOL of patients with DIE and colorectal involvement. Moreover, this pilot study can serve to determine power calculations for future randomized trials.
OBJECTIVE: A prospective pilot study to evaluate the potential role of osteopathic manipulative therapy (OMT) on quality of life (QOL) of patients with Deep Infiltrating Endometriosis (DIE) and colorectal involvement. STUDY DESIGN: Twenty patients with DIE and colorectal infiltration completed the SF-36 QOL questionnaire before and after undergoing OMT. RESULTS: The median age (range) of the patients was 30.4 years (22-39). Thirty-five percent of the patients had undergone previous surgery for endometriosis and 70% were on medical treatment. Fifteen of the 20 patients (75%) completed the protocol. There was no difference in the epidemiological characteristics or in the pre-OMT Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36 questionnaire between patients who completed the protocol or not. After a mean period of 24 days (15-53), a significant improvement in PCS (p=0.03) and MCS (p=0.0009) compared to pre-OMT values was observed giving a success rate of 80% and 60% in intention-to-treat, respectively. CONCLUSION: Our results support that OMT can improve QOL of patients with DIE and colorectal involvement. Moreover, this pilot study can serve to determine power calculations for future randomized trials.
Authors: M Sillem; I Juhasz-Böss; I Klausmeier; S Mechsner; F Siedentopf; E Solomayer Journal: Geburtshilfe Frauenheilkd Date: 2016-09 Impact factor: 2.915
Authors: Laura Buggio; Giussy Barbara; Federica Facchin; Maria Pina Frattaruolo; Giorgio Aimi; Nicola Berlanda Journal: Int J Womens Health Date: 2017-05-02