Roberta F Carvalho1, Glorimar Rosa2, Grazielle V B Huguenin1, Ronir R Luiz3, Annie S B Moreira4, Glaucia M M Oliveira1. 1. Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br. 2. Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro. Department of Nutrition and Dietetics, Josué de Castro Nutrition Institute, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br. 3. Institute of Public Health Studies, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br. 4. Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro. Dyslipidemia and Atherosclerosis of Ambulatório, National Institute of Cardiology. Brazil.. glorimar@nutricao.ufrj.br.
Abstract
BACKGROUND: Selenium (Se) is an essential micronutrient that performs physiological functions in the metabolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascular disease. AIM: To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients. METHODS: Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropometric measurements were taken, and dietary Se intake was investigated. RESULTS: Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 µg/L. Patients with plasma Se ≥ 95 µg/L were found to have a higher body mass index (BMI) (30.74 ± 4.31 vs 27.68 ± 5.63 kg/m2, P = 0.02) and waist-to-height ratio (0.65 ± 0.05 vs 0.59 ± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 µg/L. Se intake associated positively with T3L/T4L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02). CONCLUSION: The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we investigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positive association between Se intake and the most metabolically active form of the thyroid hormones. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
BACKGROUND:Selenium (Se) is an essential micronutrient that performs physiological functions in the metabolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascular disease. AIM: To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients. METHODS: Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropometric measurements were taken, and dietary Se intake was investigated. RESULTS: Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 µg/L. Patients with plasma Se ≥ 95 µg/L were found to have a higher body mass index (BMI) (30.74 ± 4.31 vs 27.68 ± 5.63 kg/m2, P = 0.02) and waist-to-height ratio (0.65 ± 0.05 vs 0.59 ± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 µg/L. Se intake associated positively with T3L/T4L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02). CONCLUSION: The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we investigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positive association between Se intake and the most metabolically active form of the thyroid hormones. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
Authors: Janaina S da Silva; Alessandra F Rosa; Cristina T Moncau; Bárbara Silva-Vignato; Silvana Marina P Pugine; Mariza P de Melo; João Marcelo D Sanchez; Marcus Antonio Zanetti Journal: J Anim Sci Date: 2021-12-01 Impact factor: 3.159