A Boucher1, P Puech2, D Kharroubi3, T Boyer4, G Lefèvre5, A Charpentier6, M Cliquennois1, C Rose7. 1. Service d'onco-hématologie, hôpital Saint-Vincent-de-Paul, université catholique de Lille, université Lille Nord de France, 59000 Lille, France. 2. Service de radiologie, CHRU de Lille, université Lille Nord de France, 59000 Lille, France. 3. Service de médecine nucléaire, CHRU de Lille, université Lille Nord de France, 59000 Lille, France. 4. Laboratoire d'hématologie, CHRU de Lille, université Lille Nord de France, 59000 Lille, France. 5. Service de médecine interne, CHRU de Lille, université Lille Nord de France, 59000 Lille, France. 6. Laboratoire d'hématologie, hôpital Saint-Vincent-de-Paul, université catholique de Lille, université Lille Nord de France, 59000 Lille, France. 7. Service d'onco-hématologie, hôpital Saint-Vincent-de-Paul, université catholique de Lille, université Lille Nord de France, 59000 Lille, France. Electronic address: rose.christian@ghicl.net.
Abstract
INTRODUCTION: Myelolipomas and extramedullary hematopoietic tumors are uncommon benign tumors. They are variably composed of mature adipose tissue and hematopoietic tissue. Myelolipoma is usually observed in the adrenal gland and extramedullary hematopoietic tumors in the liver and spleen but may occasionally be found within solid tumors. CASE REPORT: A 62-year-old man without previous haematological history presented with a voluminous solitary bilateral renal tumor. Contrast-enhanced ultrasound CT-scan and scintigraphy with technetium-99m-nanocolloid and indium-111-chloride bone marrow were highly suggestive of extramedullary hematopoietic tumor. CT-guided biopsy suggested a diagnosis of myelolipoma. An atypical hereditary spherocytosis, undiagnosed until now, was demonstrated. CONCLUSION: We report, for the first time to our knowledge, a border form between extramedullary hematopoiesis tumor and myelolipoma of renal localisation revealing a hereditary spherocytosis in an adult patient.
INTRODUCTION:Myelolipomas and extramedullary hematopoietic tumors are uncommon benign tumors. They are variably composed of mature adipose tissue and hematopoietic tissue. Myelolipoma is usually observed in the adrenal gland and extramedullary hematopoietic tumors in the liver and spleen but may occasionally be found within solid tumors. CASE REPORT: A 62-year-old man without previous haematological history presented with a voluminous solitary bilateral renal tumor. Contrast-enhanced ultrasound CT-scan and scintigraphy with technetium-99m-nanocolloid and indium-111-chloride bone marrow were highly suggestive of extramedullary hematopoietic tumor. CT-guided biopsy suggested a diagnosis of myelolipoma. An atypical hereditary spherocytosis, undiagnosed until now, was demonstrated. CONCLUSION: We report, for the first time to our knowledge, a border form between extramedullary hematopoiesis tumor and myelolipoma of renal localisation revealing a hereditary spherocytosis in an adult patient.
Authors: Poh Shean Wong; Lit Sin Yong; Nor Afidah Binti Karim; Ee Leng Gan; See Guan Toh; Noor Lita Binti Adam Journal: J ASEAN Fed Endocr Soc Date: 2021-04-17