Literature DB >> 25794500

Biological potential of carbazole derivatives.

Agata Głuszyńska1.   

Abstract

Carbazole skeleton is the key structural motif of many biologically active compounds including synthetic and natural products. Over the past several years, a large number of research highlighting the significance of carbazole derivatives has been reported in the literature. The present review focuses on the recent progress, from 2010 until now, in knowledge on various biological properties of classical, tricyclic carbazole derivatives.
Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Antimicrobial activity; Antitumor activity; Biological potential; Carbazole derivatives; DNA; Neurological disorders

Mesh:

Substances:

Year:  2015        PMID: 25794500     DOI: 10.1016/j.ejmech.2015.02.059

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  20 in total

1.  Hexadehydro-Diels-Alder (HDDA)-Enabled Carbazolyne Chemistry: Single Step, de Novo Construction of the Pyranocarbazole Core of Alkaloids of the Murraya koenigii (Curry Tree) Family.

Authors:  Tao Wang; Thomas R Hoye
Journal:  J Am Chem Soc       Date:  2016-10-13       Impact factor: 15.419

2.  Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents.

Authors:  Cornelis P Vlaar; Linette Castillo-Pichardo; Julia I Medina; Cathyria M Marrero-Serra; Ericka Vélez; Zulma Ramos; Eliud Hernández
Journal:  Bioorg Med Chem       Date:  2018-01-11       Impact factor: 3.641

3.  Bromomethylthioindole Inspired Carbazole Hybrids as Promising Class of Anti-MRSA Agents.

Authors:  Chia-Yi Cheng; Chun-Ping Chang; Tsai-Ling Yang Lauderdale; Guann-Yi Yu; Jinq-Chyi Lee; Yi-Wun Jhang; Chien-Huang Wu; Yi-Yu Ke; Amit A Sadani; Ching-Fang Yeh; I-Wen Huang; Yi-Ping Kuo; De-Jiun Tsai; Teng-Kuang Yeh; Chen-Tso Tseng; Jen-Shin Song; Yu-Wei Liu; Lun K Tsou; Kak-Shan Shia
Journal:  ACS Med Chem Lett       Date:  2016-10-21       Impact factor: 4.345

4.  Potential Antimicrobial Isopropanol-Conjugated Carbazole Azoles as Dual Targeting Inhibitors of Enterococcus faecalis.

Authors:  Yuan Zhang; Vijai Kumar Reddy Tangadanchu; Yu Cheng; Ren-Guo Yang; Jian-Mei Lin; Cheng-He Zhou
Journal:  ACS Med Chem Lett       Date:  2018-02-05       Impact factor: 4.345

5.  Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment.

Authors:  Sergey O Bachurin; Elena F Shevtsova; Galina F Makhaeva; Vladimir V Grigoriev; Natalia P Boltneva; Nadezhda V Kovaleva; Sofya V Lushchekina; Pavel N Shevtsov; Margarita E Neganova; Olga M Redkozubova; Elena V Bovina; Alexey V Gabrelyan; Vladimir P Fisenko; Vladimir B Sokolov; Alexey Yu Aksinenko; Valentina Echeverria; George E Barreto; Gjumrakch Aliev
Journal:  Sci Rep       Date:  2017-03-30       Impact factor: 4.379

6.  Selectivity in the Elaboration of Bicyclic Borazarenes.

Authors:  Ayan Bhattacharjee; Geraint H M Davies; Borna Saeednia; Steven R Wisniewski; Gary A Molander
Journal:  Adv Synth Catal       Date:  2020-12-23       Impact factor: 5.837

7.  Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives.

Authors:  Lan-Xiang Liu; Xue-Quan Wang; Bei Zhou; Li-Juan Yang; Yan Li; Hong-Bin Zhang; Xiao-Dong Yang
Journal:  Sci Rep       Date:  2015-08-19       Impact factor: 4.379

8.  Carbazole Derivatives' Binding to c-KIT G-Quadruplex DNA.

Authors:  Agata Głuszyńska; Bernard Juskowiak; Martyna Kuta-Siejkowska; Marcin Hoffmann; Shozeb Haider
Journal:  Molecules       Date:  2018-05-10       Impact factor: 4.411

9.  Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent.

Authors:  Agnieszka Chylewska; Aleksandra M Dąbrowska; Sandra Ramotowska; Natalia Maciejewska; Mateusz Olszewski; Maciej Bagiński; Mariusz Makowski
Journal:  Sci Rep       Date:  2020-07-16       Impact factor: 4.379

10.  N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation.

Authors:  Maria Stefania Sinicropi; Domenico Iacopetta; Camillo Rosano; Rosario Randino; Anna Caruso; Carmela Saturnino; Noemi Muià; Jessica Ceramella; Francesco Puoci; Manuela Rodriquez; Pasquale Longo; Maria Rosaria Plutino
Journal:  J Enzyme Inhib Med Chem       Date:  2018-12       Impact factor: 5.051

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