Literature DB >> 25794433

Fueling up skeletal muscle to reduce obesity: A TrkB story.

Ji Youn Youn1, Hua Cai2.   

Abstract

Targeting TrkB signaling could represent a good therapeutic strategy to prevent obesity. In this issue of Chemistry & Biology, Chan et al. report the efficacy of 7,8-DHT, a TrkB agonist, in preventing obesity in female mice. The underlying molecular mechanisms behind this activity seem to involve increased energy expenditure in skeletal muscle.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25794433      PMCID： PMC4817994          DOI： 10.1016/j.chembiol.2015.03.004

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  8 in total

Review 1.  Muscles, exercise and obesity: skeletal muscle as a secretory organ.

Authors:  Bente K Pedersen; Mark A Febbraio
Journal:  Nat Rev Endocrinol       Date:  2012-04-03       Impact factor: 43.330

Review 2.  Skeletal muscle mitochondrial uncoupling, adaptive thermogenesis and energy expenditure.

Authors:  Sjoerd A A van den Berg; Wouter van Marken Lichtenbelt; Ko Willems van Dijk; Patrick Schrauwen
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2011-05       Impact factor: 4.294

3.  Brain-derived neurotrophic factor correlated with muscle strength in subjects undergoing stationary bicycle exercise training.

Authors:  Sen-Wei Tsai; Yin-Ching Chan; Francois Liang; Chiann-Yi Hsu; I-Te Lee
Journal:  J Diabetes Complications       Date:  2015-02-07       Impact factor: 2.852

4.  Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice.

Authors:  B Li; L A Nolte; J S Ju; D H Han; T Coleman; J O Holloszy; C F Semenkovich
Journal:  Nat Med       Date:  2000-10       Impact factor: 53.440

5.  A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.

Authors:  Sung-Wuk Jang; Xia Liu; Manuel Yepes; Kennie R Shepherd; Gary W Miller; Yang Liu; W David Wilson; Ge Xiao; Bruno Blanchi; Yi E Sun; Keqiang Ye
Journal:  Proc Natl Acad Sci U S A       Date:  2010-01-25       Impact factor: 11.205

Review 6.  BDNF mediates adaptive brain and body responses to energetic challenges.

Authors:  Krisztina Marosi; Mark P Mattson
Journal:  Trends Endocrinol Metab       Date:  2013-12-19       Impact factor: 12.015

7.  Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase.

Authors:  V B Matthews; M-B Aström; M H S Chan; C R Bruce; K S Krabbe; O Prelovsek; T Akerström; C Yfanti; C Broholm; O H Mortensen; M Penkowa; P Hojman; A Zankari; M J Watt; H Bruunsgaard; B K Pedersen; M A Febbraio
Journal:  Diabetologia       Date:  2009-04-22       Impact factor: 10.122

8.  Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function.

Authors:  Helen Karakelides; Brian A Irving; Kevin R Short; Peter O'Brien; K Sreekumaran Nair
Journal:  Diabetes       Date:  2009-10-15       Impact factor: 9.461
  8 in total
  3 in total

1.  AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration.

Authors:  Xing Fu; Mei-Jun Zhu; Mike V Dodson; Min Du
Journal:  J Biol Chem       Date:  2015-09-14       Impact factor: 5.157

2.  Moderately decreased maternal dietary energy intake during pregnancy reduces fetal skeletal muscle mitochondrial biogenesis in the pigs.

Authors:  Tiande Zou; Bing Yu; Jie Yu; Xiangbing Mao; Ping Zheng; Jun He; Zhiqing Huang; Yue Liu; Daiwen Chen
Journal:  Genes Nutr       Date:  2016-06-23       Impact factor: 5.523

3.  Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK.

Authors:  Xing Fu; Meijun Zhu; Shuming Zhang; Marc Foretz; Benoit Viollet; Min Du
Journal:  Diabetes       Date:  2015-09-17       Impact factor: 9.461
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.