Literature DB >> 2579383

Evidence for widespread effects of noradrenaline on axon terminals in the rat frontal cortex.

P Mobley, P Greengard.   

Abstract

Noradrenaline, apparently working through activation of beta-adrenergic receptors, alters the state of phosphorylation of a substantial proportion of synapsin I in rat frontal cortex. Since synapsin I is enriched in virtually all axon terminals in this brain region, the results indicate that noradrenaline, a sparsely distributed neurotransmitter, affects a large number of axon terminals in this region. The results also suggest that noradrenaline receptors are present on a substantial percentage of all axon terminals in the cerebral cortex, despite the low density of noradrenergic fibers present. The data support the view that noradrenaline may serve a paracrine function.

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Year:  1985        PMID： 2579383      PMCID： PMC397164          DOI： 10.1073/pnas.82.3.945

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  20 in total

1.  Noradrenergic axon terminals in the cerebral cortex of rat. III. Topometric ultrastructural analysis.

Authors:  L Descarries; K C Watkins; Y Lapierre
Journal:  Brain Res       Date:  1977-09-16       Impact factor: 3.252

2.  5-Hydroxytryptamine and noradrenaline in the hippocampal region: effect of transection of afferent pathways on endogenous levels, high affinity uptake and some transmitter-related enzymes.

Authors:  J Storm-Mathisen; H C Guldberg
Journal:  J Neurochem       Date:  1974-05       Impact factor: 5.372

3.  Modulatory actions of norepinephrine in the central nervous system.

Authors:  D J Woodward; H C Moises; B D Waterhouse; B J Hoffer; R Freedman
Journal:  Fed Proc       Date:  1979-06

4.  Noradrenergic axon terminals in the cerebral cortex of rat. II. Quantitative data revealed by light and electron microscope radioautography of the frontal cortex.

Authors:  Y Lapierre; A Beaudet; N Demianczuk; L Descarries
Journal:  Brain Res       Date:  1973-12-07       Impact factor: 3.252

5.  Depolarizing agents and cyclic nucleotides regulate the phosphorylation of specific neuronal proteins in rat cerebral cortex slices.

Authors:  J Forn; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

6.  Norepinephrine stimulated cyclic AMP accumulation in rat limbic forebrain slices: partial mediation by a subpopulation of receptors with neither alpha nor beta characteristics.

Authors:  P L Mobley; F Sulser
Journal:  Eur J Pharmacol       Date:  1979-12-07       Impact factor: 4.432

7.  Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.

Authors:  W B Huttner; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

8.  Depolarization-induced phosphorylation of specific proteins, mediated by calcium ion influx, in rat brain synaptosomes.

Authors:  B K Krueger; J Forn; P Greengard
Journal:  J Biol Chem       Date:  1977-04-25       Impact factor: 5.157

9.  Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. I. Solubilization, purification, and some properties of an endogenous phosphoprotein.

Authors:  T Ueda; P Greengard
Journal:  J Biol Chem       Date:  1977-07-25       Impact factor: 5.157

10.  Characteristics of dopamine and beta-adrenergic sensitive adenylate cyclases in the frontal cerebral cortex of the rat. Comparative effects of neuroleptics on frontal cortex and striatal dopamine sensitive adenylate cyclases.

Authors:  J Bockaert; J P Tassin; A M Thierry; J Glowinski; J Premont
Journal:  Brain Res       Date:  1977-02-11       Impact factor: 3.252
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  11 in total

1.  Adrenergic regulation of intercellular communications between cultured striatal astrocytes from the mouse.

Authors:  C Giaume; P Marin; J Cordier; J Glowinski; J Premont
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-01       Impact factor: 11.205

2.  Binding of psychoactive drugs to rat brain amine receptors, measured ex vivo, and their effects on the metabolism of biogenic amines.

Authors:  H R Burki
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-03       Impact factor: 3.000

3.  Clonidine inhibits the isoproterenol-induced desensitization of the beta noradrenergic activated adenylate cyclase system in astrocytes.

Authors:  W J Northam; P L Mobley
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 4.  Neuronal phosphoproteins. Mediators of signal transduction.

Authors:  P Greengard
Journal:  Mol Neurobiol       Date:  1987 Spring-Summer       Impact factor: 5.590

5.  Synaptic investment of striatal cellular domains by grafted dopamine neurons in weaver mutant mice.

Authors:  L C Triarhou; W C Low; B Ghetti
Journal:  Naturwissenschaften       Date:  1987-12

Review 6.  The structure and mechanism of neurotransmitter receptors. Implications for the structure and function of the central nervous system.

Authors:  P G Strange
Journal:  Biochem J       Date:  1988-01-15       Impact factor: 3.857

7.  Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory.

Authors:  Mara Mather; David Clewett; Michiko Sakaki; Carolyn W Harley
Journal:  Behav Brain Sci       Date:  2015-07-01       Impact factor: 12.579

8.  Norepinephrine and isoproterenol increase the phosphorylation of synapsin I and synapsin II in dentate slices of young but not aged Fisher 344 rats.

Authors:  K D Parfitt; B J Hoffer; M D Browning
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

9.  Growth and differentiation of cerebellar suspensions transplanted into the adult cerebellum of mice with heredodegenerative ataxia.

Authors:  C Sotelo; R M Alvarado-Mallart
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

10.  Long-lasting hippocampal synaptic protein loss in a mouse model of posttraumatic stress disorder.

Authors:  Leonie Herrmann; Irina A Ionescu; Kathrin Henes; Yulia Golub; Nancy Xin Ru Wang; Dominik R Buell; Florian Holsboer; Carsten T Wotjak; Ulrike Schmidt
Journal:  PLoS One       Date:  2012-08-10       Impact factor: 3.240
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