| Literature DB >> 25793228 |
F C Wu1, Y Wu, Z Niu, F Vollmer.
Abstract
A label-free method is developed to ratiometrically determine the stoichiometry of oligonucleotides attached to the surface of gold nanoparticle (GNP) by whispering gallery mode biosensing. Utilizing this scheme, it is furthermore shown that the stoichiometric ratio of GNP attached oligonucleotide species can be controlled by varying the concentration ratio of thiolated oligonucleotides that are used to modify the GNP.Entities:
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Year: 2015 PMID: 25793228 PMCID: PMC4609311 DOI: 10.1039/c5an00179j
Source DB: PubMed Journal: Analyst ISSN: 0003-2654 Impact factor: 4.616