Literature DB >> 25791764

Showering effectiveness for human hair decontamination of the nerve agent VX.

Denis Josse1, Julien Wartelle2, Catherine Cruz2.   

Abstract

In this work, our goals were to establish whether hair decontamination by showering one hour post-exposure to the highly toxic organophosphate nerve agent VX was effective, whether it required the addition of a detergent to water and, if it could be improved by using the adsorbent Fuller's Earth (FE) or the Reactive Skin Decontamination Lotion (RSDL) 30 min prior to showering. Hair exposure to VX and decontamination was performed by using an in vitro model. Hair showering led to 72% reduction of contamination. Addition of detergent to water slightly increased the decontamination effectiveness. Hair treatment with FE or RSDL improved the decontamination rate. Combination of FE use and showering, which yielded a decontamination factor of 41, was demonstrated to be the most effective hair decontamination procedure. Hair wiping after showering was shown to contribute to hair decontamination. Altogether, our results highlighted the importance of considering hair decontamination as an important part of body surface decontamination protocols.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Hair decontamination; Showering; VX nerve agent

Mesh:

Substances:

Year:  2015        PMID: 25791764     DOI: 10.1016/j.cbi.2015.03.010

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN: 0009-2797            Impact factor:   5.192


  4 in total

1.  Hybrid in vitro diffusion cell for simultaneous evaluation of hair and skin decontamination: temporal distribution of chemical contaminants.

Authors:  Hazem Matar; Nevine Amer; Sneha Kansagra; Andreia Pinhal; Elliot Thomas; Scott Townend; Joanne Larner; Robert P Chilcott
Journal:  Sci Rep       Date:  2018-11-15       Impact factor: 4.379

2.  Mass Casualty Decontamination in a Chemical or Radiological/Nuclear Incident with External Contamination: Guiding Principles and Research Needs.

Authors:  Susan M Cibulsky; Danny Sokolowski; Marc Lafontaine; Christine Gagnon; Peter G Blain; David Russell; Helmut Kreppel; Walter Biederbick; Takeshi Shimazu; Hisayoshi Kondo; Tomoya Saito; Jean-René Jourdain; Francois Paquet; Chunsheng Li; Makoto Akashi; Hideo Tatsuzaki; Lesley Prosser
Journal:  PLoS Curr       Date:  2015-11-02

Review 3.  Mass Casualty Decontamination for Chemical Incidents: Research Outcomes and Future Priorities.

Authors:  Samuel Collins; Thomas James; Holly Carter; Charles Symons; Felicity Southworth; Kerry Foxall; Tim Marczylo; Richard Amlôt
Journal:  Int J Environ Res Public Health       Date:  2021-03-17       Impact factor: 3.390

4.  Human volunteer study of the decontamination of chemically contaminated hair and the consequences for systemic exposure.

Authors:  Samuel Collins; Thomas James; Felicity Southworth; Louise Davidson; Natalie Williams; Emily Orchard; Tim Marczylo; Richard Amlôt
Journal:  Sci Rep       Date:  2020-11-30       Impact factor: 4.996

  4 in total

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