| Literature DB >> 25791514 |
Annemarie Greife1, Michèle J Hoffmann1, Wolfgang A Schulz2.
Abstract
The Notch pathway, which controls stem cell maintenance and cell differentiation, is activated in certain cancers and therefore constitutes a therapeutic target. Especially in invasive urothelial carcinoma, the pathway is inactivated instead, and drugs inhibiting Notch signaling are likely contra-indicated.Entities:
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Year: 2015 PMID： 25791514 DOI： 10.1016/j.eururo.2015.02.034
Source DB: PubMed Journal: Eur Urol ISSN： 0302-2838 Impact factor: 20.096