| Literature DB >> 25790033 |
Xuan Wu1, Yan Li, Chen Lin, Xiao-Yu Hu, Leyong Wang.
Abstract
Novel GSH- and pH-responsive supramolecular vesicles constructed by an amphiphilic inclusion complex formed from water-soluble pillar[5]arene and lysine derivative have been successfully developed, which can efficiently encapsulate anticancer drug MTZ and show rapid MTZ-release in a simulated acidic tumor environment with high GSH concentration, and exhibit potent antitumor activity.Entities:
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Year: 2015 PMID: 25790033 DOI: 10.1039/c5cc01393c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222