Literature DB >> 25789387

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Aydın Akyüz.   

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Year:  2015        PMID: 25789387      PMCID: PMC5336926     

Source DB:  PubMed          Journal:  Anatol J Cardiol        ISSN: 2149-2263            Impact factor:   1.596


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To the Editor, We would like to thank the authors for their comments and criticism of our original investigation (1), entitled “Heart rate recovery may predict the presence of coronary artery disease,” published in Anatolian J Cardiol 2014; 14: 351-6. We wrote in the methodology section that “post-exercise HRR was measured in the sitting position during the cool-down period after the cessation of peak exercise.” “Cooling down” commonly refers to easy exercise following strenuous exercise. In contrast, the “cool-down period” refers to the length of the warming-down time. In the manuscript, the phrase “during the cool-down period after the cessation of peak exercise” means during the length of early recovery time after peak exercise. We retrospectively enrolled subjects in the sitting position during the recovery phase who had exercise testing abruptly terminated. The values of ≤12 beats/min in the first minute after exercise for protocols that use a post-exercise cool-down and of ≤18 beats/min in the first minute postexercise for protocols that stop exercise abruptly have prognostic value, especially in predicting mortality (2, 3). However, these two values were generally not accepted for determining the presence of coronary artery disease (CAD). Georgoulias et al. (4) used an HRR1 of ≤21 beats/min after abruptly stopping exercise for determining the presence CAD. Hence, an HRR1 value of ≤18 beats/min might arguably determine the presence of CAD. After we used ROC analysis in Metlab software (Version 12.5.0, Ostend, Belgium) to determine the best HRR1 value, we obtained a value of ≤21/beats/min as the best specificity and sensitivity point for predicting CAD. The main aim of the study was to investigate an HRR1 value of ≤21 beats/min for determining the presence of CAD but not heart rate reserve. We mentioned heart rate reserve as an exercise testing parameter in the manuscript. We calculated heart rate reserve as 220 - age in years - resting heart rate in beats/min. If we had defined heart rate reserve in the methods, it would have made a better manuscript.
  4 in total

1.  Heart rate recovery may predict the presence of coronary artery disease.

Authors:  Aydin Akyüz; Seref Alpsoy; Dursun Cayan Akkoyun; Hasan Değirmenci; Niyazi Güler
Journal:  Anadolu Kardiyol Derg       Date:  2014-01-02

2.  Heart-rate recovery immediately after exercise as a predictor of mortality.

Authors:  C R Cole; E H Blackstone; F J Pashkow; C E Snader; M S Lauer
Journal:  N Engl J Med       Date:  1999-10-28       Impact factor: 91.245

3.  Heart rate recovery immediately after treadmill exercise and left ventricular systolic dysfunction as predictors of mortality: the case of stress echocardiography.

Authors:  J Watanabe; M Thamilarasan; E H Blackstone; J D Thomas; M S Lauer
Journal:  Circulation       Date:  2001-10-16       Impact factor: 29.690

4.  Abnormal heart rate recovery immediately after treadmill testing: correlation with clinical, exercise testing, and myocardial perfusion parameters.

Authors:  Panagiotis Georgoulias; Alexandros Orfanakis; Nikolaos Demakopoulos; Petros Xaplanteris; Georgios Mortzos; Panos Vardas; Nikolaos Karkavitsas
Journal:  J Nucl Cardiol       Date:  2003 Sep-Oct       Impact factor: 5.952

  4 in total

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