| Literature DB >> 25788550 |
Hein Trip1, Katrin Mende2, Joanna A Majchrzykiewicz-Koehorst3, Norbert J A Sedee3, Albert G Hulst3, Hugo-Jan Jansen4, Clinton K Murray2, Armand Paauw3.
Abstract
Shotgun proteomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) was applied to detect β-lactamases in clinical Acinetobacter baumannii isolates. The correlation of the detection of β-lactamase proteins (rather than PCR detection of the corresponding genes) with the resistance phenotypes demonstrated an added value for LC-MS/MS in antimicrobial susceptibility testing.Entities:
Mesh:
Substances:
Year: 2015 PMID: 25788550 PMCID: PMC4432071 DOI: 10.1128/JCM.00620-15
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948