Literature DB >> 25788235

In vivo imaging of the cannabinoid CB1 receptor with positron emission tomography.

J Hirvonen1,2.   

Abstract

Positron emission tomography (PET) can visualize and quantify receptors and other targets in the living human brain, and recent progress in radioligand development has enabled measurement of cannabinoid type-1 (CB1 ) receptors. Cannabinoid CB1 receptors have been implicated in multiple human diseases, such as obesity, mood disorders, and addiction. First in vivo human studies have shown distinctive spatial and temporal alterations in cannabinoid CB1 receptor binding in addictive disorders.
© 2015 American Society for Clinical Pharmacology and Therapeutics.

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Year:  2015        PMID： 25788235     DOI： 10.1002/cpt.116

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  3 in total

1.  Decreased Cannabinoid CB1 Receptors in Male Tobacco Smokers Examined With Positron Emission Tomography.

Authors:  Jussi Hirvonen; Paolo Zanotti-Fregonara; David A Gorelick; Chul Hyoung Lyoo; Denise Rallis-Frutos; Cheryl Morse; Sami S Zoghbi; Victor W Pike; Nora D Volkow; Marilyn A Huestis; Robert B Innis
Journal:  Biol Psychiatry       Date:  2018-07-21       Impact factor: 13.382

Review 2.  Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development.

Authors:  Lu Hou; Jian Rong; Ahmed Haider; Daisuke Ogasawara; Cassis Varlow; Michael A Schafroth; Linjing Mu; Jiefeng Gan; Hao Xu; Christopher J Fowler; Ming-Rong Zhang; Neil Vasdev; Simon Ametamey; Benjamin F Cravatt; Lu Wang; Steven H Liang
Journal:  J Med Chem       Date:  2020-12-30       Impact factor: 7.446

Review 3.  Endocannabinoid signaling in psychiatric disorders: a review of positron emission tomography studies.

Authors:  Matthew E Sloan; Caroline W Grant; Joshua L Gowin; Vijay A Ramchandani; Bernard Le Foll
Journal:  Acta Pharmacol Sin       Date:  2018-08-30       Impact factor: 6.150
  3 in total

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