E Şenel1, Y Yuyucu Karabulut2, S Doğruer Şenel3. 1. Faculty of Medicine, Department of Dermatology, Hitit University, Çorum, Turkey. 2. Faculty of Medicine, Department of Pathology, Mersin University, Mersin, Turkey. 3. Faculty of Economics, Department of Public Administration, Anadolu University, Eskişehir, Turkey.
Abstract
BACKGROUND: Dermatology literature lacks a study investigating both histopathological and dermatoscopic features of dermatofibroma. OBJECTIVE: To analyse histopathological, dermatoscopic and digital microscopic features of dermatofibromas. METHODS: Two hundred dermatofibromas and 190 patients were included and retrospectively evaluated. Nine histopathological and ten dermatoscopic patterns were used to classify the lesions. We identified four different types of dermatofibroma in digital microscopy. RESULTS: The mean age of the patients was 42.18 ± 13.72 years. Dermatofibroma was more common in females (67%) and the male to female ratio was 1:1.97. The most common location was leg (41%). The most frequent histopathological variant was fibrocollagenous type (49%). Grenz zone was the most common histopathological finding (89%). The most frequent digital microscopic type was type 1 (63%). CONCLUSIONS: We found that palisading variant displayed only pattern 6 in dermatoscopy and cellular variant showed type 3 significantly in digital microscopy.
BACKGROUND: Dermatology literature lacks a study investigating both histopathological and dermatoscopic features of dermatofibroma. OBJECTIVE: To analyse histopathological, dermatoscopic and digital microscopic features of dermatofibromas. METHODS: Two hundred dermatofibromas and 190 patients were included and retrospectively evaluated. Nine histopathological and ten dermatoscopic patterns were used to classify the lesions. We identified four different types of dermatofibroma in digital microscopy. RESULTS: The mean age of the patients was 42.18 ± 13.72 years. Dermatofibroma was more common in females (67%) and the male to female ratio was 1:1.97. The most common location was leg (41%). The most frequent histopathological variant was fibrocollagenous type (49%). Grenz zone was the most common histopathological finding (89%). The most frequent digital microscopic type was type 1 (63%). CONCLUSIONS: We found that palisading variant displayed only pattern 6 in dermatoscopy and cellular variant showed type 3 significantly in digital microscopy.
Authors: Khadijeh Jahanseir; Deyin Xing; Patricia T Greipp; William R Sukov; Gary L Keeney; Brooke E Howitt; J Kenneth Schoolmeester Journal: Int J Gynecol Pathol Date: 2018-11 Impact factor: 2.762