Literature DB >> 2578668

Murine monoclonal antibodies to the myelin-associated glycoprotein react with large granular lymphocytes of human blood.

M J Dobersen, P Gascon, S Trost, J A Hammer, S Goodman, A B Noronha, D J O'Shannessy, R O Brady, R H Quarles.   

Abstract

Monoclonal antibodies prepared to human myelin-associated glycoprotein were shown to react with a population of human peripheral blood mononuclear cells. The population is similar to the large granular lymphocytes or natural killer cells defined by antibody Leu 7 (also called HNK-1). The population also includes cells exhibiting the Leu 2 marker for suppressor/cytotoxic T cells. The results indicate a shared antigenicity between the nervous system and the immune system and may be relevant to the pathogenesis of demyelinating diseases.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2578668      PMCID： PMC397078          DOI： 10.1073/pnas.82.2.552

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  28 in total

1.  Biochemical characterisation and localization in brain of a human brain-leucocyte membrane glycoprotein recognised by a monoclonal antibody.

Authors:  J L McKenzie; R Dalchau; J W Fabre
Journal:  J Neurochem       Date:  1982-11       Impact factor: 5.372

2.  Decreased NK killing in patients with multiple sclerosis: an analysis on the level of the single effector cell in peripheral blood and cerebrospinal fluid in relation to the activity in the disease.

Authors:  J Merrill; M Jondal; J Seeley; M Ullberg; A Sidén
Journal:  Clin Exp Immunol       Date:  1982-02       Impact factor: 4.330

3.  Neuroimmunology I: Immunoregulation in neurological disease.

Authors:  H L Weiner; S L Hauser
Journal:  Ann Neurol       Date:  1982-05       Impact factor: 10.422

4.  A shared antigenic determinant between natural killer cells and nervous tissue.

Authors:  S Schuller-Petrovic; W Gebhart; H Lassmann; H Rumpold; D Kraft
Journal:  Nature       Date:  1983 Nov 10-16       Impact factor: 49.962

5.  Myelin-associated glycoprotein is the antigen for a monoclonal IgM in polyneuropathy.

Authors:  P E Braun; D E Frail; N Latov
Journal:  J Neurochem       Date:  1982-11       Impact factor: 5.372

6.  Endogenous and interferon-augmented natural killer cell activity of human peripheral blood mononuclear cells in vitro. Studies of patients with multiple sclerosis, systemic lupus erythematosus or rheumatoid arthritis.

Authors:  P A Neighbour; A I Grayzel; A E Miller
Journal:  Clin Exp Immunol       Date:  1982-07       Impact factor: 4.330

7.  Demyelinating neuropathy and monoclonal IgM antibody to myelin-associated glycoprotein.

Authors:  A J Steck; N Murray; C Meier; N Page; G Perruisseau
Journal:  Neurology       Date:  1983-01       Impact factor: 9.910

8.  Suppressor cell function of human granular lymphocytes identified by the HNK-1 (Leu 7) monoclonal antibody.

Authors:  A B Tilden; T Abo; C M Balch
Journal:  J Immunol       Date:  1983-03       Impact factor: 5.422

9.  Multiple sclerosis: distribution of T cell subsets within active chronic lesions.

Authors:  U Traugott; E L Reinherz; C S Raine
Journal:  Science       Date:  1983-01-21       Impact factor: 47.728

10.  Indication of a possible role in a demyelinating neuropathy for an antigen shared between myelin and NK cells.

Authors:  N Murray; A J Steck
Journal:  Lancet       Date:  1984-03-31       Impact factor: 79.321
View more
  11 in total

1.  Leu 7 immunoreactivity in fetal olfactory epithelium and dysplastic or neoplastic olfactory lesions induced in Syrian golden hamsters by N-nitrosodiethylamine.

Authors:  J M Ward
Journal:  Am J Pathol       Date:  1986-05       Impact factor: 4.307

Review 2.  Differential expression of glial- and neuronal-associated antigens in human tumors of the central and peripheral nervous system.

Authors:  G Reifenberger; J Szymas; W Wechsler
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

3.  Generation and characterization of mouse monoclonal antibodies to the myelin-associated glycoprotein (MAG).

Authors:  M J Dobersen; J A Hammer; A B Noronha; T D MacIntosh; B D Trapp; R O Brady; R H Quarles
Journal:  Neurochem Res       Date:  1985-04       Impact factor: 3.996

4.  Immunoreactivity for Leu-7 in neurofibrosarcoma and other spindle cell sarcomas of soft tissue.

Authors:  P E Swanson; J C Manivel; M R Wick
Journal:  Am J Pathol       Date:  1987-03       Impact factor: 4.307

5.  Non-specific binding of mouse myeloma IgM immunoglobulins by human myelin sheaths and astrocytes. A potential complication of nervous system immunoperoxidase histochemistry.

Authors:  E Perentes; L J Rubinstein
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

6.  Immunohistochemical recognition of human nerve sheath tumors by anti-Leu 7 (HNK-1) monoclonal antibody.

Authors:  E Perentes; L J Rubinstein
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088

Review 7.  Developmental and pathophysiological aspects of the myelin-associated glycoprotein.

Authors:  R O Brady; R H Quarles
Journal:  Cell Mol Neurobiol       Date:  1988-06       Impact factor: 5.046

8.  A syngeneic monoclonal anti-idiotype antibody against HNK-1: characterization and cytotoxic activity in vitro.

Authors:  M Schluep; N Page; D Burger; A J Steck
Journal:  Clin Exp Immunol       Date:  1989-02       Impact factor: 4.330

9.  Phylogenetically conserved antigen on nerve cells and lymphocytes resembles myelin-associated glycoprotein.

Authors:  B Peault; C L Chen; M D Cooper; M Barbu; M Lipinski; N M Le Douarin
Journal:  Proc Natl Acad Sci U S A       Date:  1987-02       Impact factor: 11.205

10.  Myelin-associated glycoprotein (MAG) and rat brain-specific 1B236 protein: mapping of epitopes and demonstration of immunological identity.

Authors:  A B Noronha; J A Hammer; C Lai; M Kiel; R J Milner; J G Sutcliffe; R H Quarles
Journal:  J Mol Neurosci       Date:  1989       Impact factor: 3.444
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.