Literature DB >> 25786587

Role of saliva in the caries experience and calculus formation of young patients undergoing hemodialysis.

Marcia Rejane Thomas Canabarro Andrade1,2, Sabrina Loren Almeida Salazar3, Leandro Figueira Reis de Sá4, Maristela Portela5, Antonio Ferreira-Pereira4, Rosangela Maria Araújo Soares4, Anna Thereza Thomé Leão6, Laura Guimarães Primo3.   

Abstract

OBJECTIVES: The aims of this study were to investigate the caries experience, periodontal status, oral hygiene habits, and salivary parameters of children and adolescents undergoing hemodialysis (HD) and to compare them with their healthy counterparts.
METHODS: Fifty-two HD patients were matched for age, sex, ethnicity, and social class with 52 healthy subjects for analysis of the number of decayed, missing and filled teeth, plaque and gingival index, dental calculus accumulation, measurements of pocket depth, clinical attachment level, gingival recession, and bleeding on probing. Stimulated saliva samples were collected to assess salivary flow rate, pH and buffer capacity, and salivary concentrations of calcium, phosphate, and urea by colorimetric method.
RESULTS: HD patients had lower dental caries (p = 0.004), greater plaque and calculus accumulation (p = 0.001), and reported flossing less often than the controls (p = 0.013). Regarding salivary analysis, HD patients showed significantly higher values of pH, buffer capacity, and salivary urea concentration when compared to the controls (p = 0.001).
CONCLUSION: HD patients had lower caries experience, higher accumulation of dental plaque, and calculus deposition than their healthy counterparts, probably due to the differences found in their salivary biochemical parameters. CLINICAL SIGNIFICANCE: A significant number of children and adolescents undergoing hemodialysis are candidates for kidney transplantation and should receive complete pre-transplant dental exams and dental treatment. Our results open the way for the development of an individualized dental protocol for these patients with preventive measures and treatment of the poor oral health in HD patients.

Entities:  

Keywords:  Calculus; Child; Dental caries; Plaque index; Renal dialysis; Saliva

Mesh:

Year:  2015        PMID: 25786587     DOI: 10.1007/s00784-015-1441-4

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  44 in total

1.  K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.

Authors: 
Journal:  Am J Kidney Dis       Date:  2002-02       Impact factor: 8.860

2.  Salivary analysis of patients with chronic renal failure undergoing hemodialysis.

Authors:  Carla Martins; Walter Luiz Siqueira; Elizabeth de Oliveira; Laura Salignac de Souza Guimarães Primo; José Nicolau
Journal:  Spec Care Dentist       Date:  2006 Sep-Oct

3.  The oral health status of dentate patients with chronic renal failure undergoing dialysis therapy.

Authors:  C P Bots; J H G Poorterman; H S Brand; H Kalsbeek; B M van Amerongen; E C I Veerman; A V Nieuw Amerongen
Journal:  Oral Dis       Date:  2006-03       Impact factor: 3.511

4.  The oral health status of individuals on renal dialysis.

Authors:  K Naugle; M L Darby; D B Bauman; L T Lineberger; R Powers
Journal:  Ann Periodontol       Date:  1998-07

5.  Dental calculus formation in children and adolescents undergoing hemodialysis.

Authors:  Carla Martins; Walter Luiz Siqueira; Elizabeth Oliveira; José Nicolau; Laura Guimarães Primo
Journal:  Pediatr Nephrol       Date:  2012-07-20       Impact factor: 3.714

Review 6.  Caries-protective factors in saliva.

Authors:  F Lagerlöf; A Oliveby
Journal:  Adv Dent Res       Date:  1994-07

Review 7.  Systemic consequences of poor oral health in chronic kidney disease patients.

Authors:  Harun Akar; Gulcan Coskun Akar; Juan Jesús Carrero; Peter Stenvinkel; Bengt Lindholm
Journal:  Clin J Am Soc Nephrol       Date:  2010-11-29       Impact factor: 8.237

8.  Chronic renal failure and periodontal disease.

Authors:  V K Kitsou; A Konstantinidis; K C Siamopoulos
Journal:  Ren Fail       Date:  2000-05       Impact factor: 2.606

Review 9.  Lower dental caries prevalence associated to chronic kidney disease: a systematic review.

Authors:  Marcia Rejane Thomas Canabarro Andrade; Lívia Azeredo Alves Antunes; Rosangela Maria de Araújo Soares; Anna Theresa Tome Leão; Luciane Cople Maia; Laura Guimarães Primo
Journal:  Pediatr Nephrol       Date:  2013-04-18       Impact factor: 3.714

10.  Problems and proposals for recording gingivitis and plaque.

Authors:  J Ainamo; I Bay
Journal:  Int Dent J       Date:  1975-12       Impact factor: 2.512

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  5 in total

1.  Assessment of the oral health status of children with chronic kidney disease.

Authors:  Berkant Sezer; Remziye Kaya; Nur Kodaman Dokumacıgil; Duygu Sıddıkoğlu; Serçin Güven; Nurdan Yıldız; Harika Alpay; Betül Kargül
Journal:  Pediatr Nephrol       Date:  2022-04-30       Impact factor: 3.714

2.  Assessment of oral health status and inflammatory markers in end stage chronic kidney disease patients: A cross-sectional study.

Authors:  Lokesh Sharma; Devina Pradhan; Rahul Srivastava; Manas Shukla; Omveer Singh
Journal:  J Family Med Prim Care       Date:  2020-05-31

3.  Effect of Exo/Endogenous Prophylaxis Dentifrice/Drug and Cariogenic Conditions of Patient on Molecular Property of Dental Biofilm: Synchrotron FTIR Spectroscopic Study.

Authors:  Pavel Seredin; Dmitry Goloshchapov; Vladimir Kashkarov; Dmitry Nesterov; Yuri Ippolitov; Ivan Ippolitov; Jitraporn Vongsvivut
Journal:  Pharmaceutics       Date:  2022-06-26       Impact factor: 6.525

4.  Pathology-specific molecular profiles of saliva in patients with multiple dental caries-potential application for predictive, preventive and personalised medical services.

Authors:  Pavel Seredin; Dmitry Goloshchapov; Yuri Ippolitov; Pimm Vongsvivut
Journal:  EPMA J       Date:  2018-04-25       Impact factor: 6.543

5.  Oro-Dental Health and Primary Nephrotic Syndrome among Vietnamese Children.

Authors:  Hang Minh Luong; Tra Thu Nguyen; Huy-Thinh Tran; Phung Thi Tran; Phuong-Nga Nguyen; Huong Thu Nguyen; Duc Minh Nguyen; Hanh Tran Thi Duc; Son Minh Tong
Journal:  Children (Basel)       Date:  2021-06-10
  5 in total

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