OBJECTIVES: The present paper aimed at reviewing literature data on the inflammatory hypothesis of mood spectrum, as well as the overlapping features with some chronic rheumatologic disorders, in particular fibromyalgia and chronic fatigue syndrome. METHODS: A literature search was carried out for English papers published in the years 2000-2014, while using the following words: mood spectrum, depression, bipolar disorders, fibromyalgia, chronic fatigue syndrome, neurotransmitters, inflammation, neuroinflammation, cytokines. RESULTS: Overlapping features were highlighted between mood spectrum, fibromyalgia and chronic fatigue syndrome suggesting common underlying mechanisms at pathophysiological level involving both central nervous and the immune systems. CONCLUSIONS: Taken together, the literature would suggest that the borders between different medical domains should be reconsidered in the light of common processes linking them.
OBJECTIVES: The present paper aimed at reviewing literature data on the inflammatory hypothesis of mood spectrum, as well as the overlapping features with some chronic rheumatologic disorders, in particular fibromyalgia and chronic fatigue syndrome. METHODS: A literature search was carried out for English papers published in the years 2000-2014, while using the following words: mood spectrum, depression, bipolar disorders, fibromyalgia, chronic fatigue syndrome, neurotransmitters, inflammation, neuroinflammation, cytokines. RESULTS: Overlapping features were highlighted between mood spectrum, fibromyalgia and chronic fatigue syndrome suggesting common underlying mechanisms at pathophysiological level involving both central nervous and the immune systems. CONCLUSIONS: Taken together, the literature would suggest that the borders between different medical domains should be reconsidered in the light of common processes linking them.
Authors: Juan P Sanabria-Mazo; Carlos G Forero; Paula Cristobal-Narváez; Carlos Suso-Ribera; Azucena García-Palacios; Ariadna Colomer-Carbonell; Adrián Pérez-Aranda; Laura Andrés-Rodríguez; Lance M McCracken; Francesco D'Amico; Pere Estivill-Rodríguez; Bernat Carreras-Marcos; Antonio Montes-Pérez; Olga Comps-Vicente; Montserrat Esteve; Mar Grasa; Araceli Rosa; Antonio I Cuesta-Vargas; Michael Maes; Xavier Borràs; Silvia Edo; Antoni Sanz; Albert Feliu-Soler; Juan R Castaño-Asins; Juan V Luciano Journal: BMJ Open Date: 2020-07-23 Impact factor: 2.692
Authors: Cristina Buigues; Julio Fernández-Garrido; Leo Pruimboom; Aldert J Hoogland; Rut Navarro-Martínez; Mary Martínez-Martínez; Yolanda Verdejo; Mari Carmen Mascarós; Carlos Peris; Omar Cauli Journal: Int J Mol Sci Date: 2016-06-14 Impact factor: 5.923
Authors: Ciro Conversano; Laura Marchi; Ciacchini Rebecca; Claudia Carmassi; Bastianina Contena; Laura Maria Bazzichi; Angelo Gemignani Journal: Clin Pract Epidemiol Ment Health Date: 2018-09-28
Authors: Miguel A Pappolla; Laxmaiah Manchikanti; Clark R Andersen; Nigel H Greig; Fawad Ahmed; Xiang Fang; Michael A Seffinger; Andrea M Trescot Journal: PLoS One Date: 2019-05-06 Impact factor: 3.240