Literature DB >> 2578558

Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials.

E O Backlund, P O Granberg, B Hamberger, E Knutsson, A Mårtensson, G Sedvall, A Seiger, L Olson.   

Abstract

Autologous adrenal medullary tissue was transplanted to the striatum in two patients with severe parkinsonism. The aim was to provide the striatum with a new cellular source of catecholamines. Some rewarding effects were registered. This is the first time that such tissue has been transplanted in the human brain. The results merit further clinical trials.

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Year:  1985        PMID: 2578558     DOI: 10.3171/jns.1985.62.2.0169

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  76 in total

1.  Caudate nucleus pathology in Parkinson's disease: ultrastructural and biochemical findings in biopsy material.

Authors:  B Lach; D Grimes; B Benoit; A Minkiewicz-Janda
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

2.  Dopaminergic differentiation of the Nurr1-expressing immortalized mesencephalic cell line CSM14.1 in vitro.

Authors:  Stefan Jean-Pierre Haas; Andreas Wree
Journal:  J Anat       Date:  2002-07       Impact factor: 2.610

Review 3.  Modulation of dopaminergic neuronal differentiation from sympathoadrenal progenitors.

Authors:  Vladimir Vukicevic; Maria F Rubin de Celis; Gabriela Diaz-Valencia; Stefan R Bornstein; Monika Ehrhart-Bornstein
Journal:  J Mol Neurosci       Date:  2012-03-25       Impact factor: 3.444

Review 4.  Cell implantation in Parkinson's disease.

Authors:  A Williams
Journal:  BMJ       Date:  1990-08-11

5.  Treatment frontiers.

Authors:  Kerri Smith
Journal:  Nature       Date:  2010-08-26       Impact factor: 49.962

Review 6.  Transplantation into the human brain: present status and future possibilities.

Authors:  O Lindvall
Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-06       Impact factor: 10.154

7.  Quo vadis, neurochirurgia paediatrica?

Authors:  K Sano
Journal:  Childs Nerv Syst       Date:  1989-02       Impact factor: 1.475

8.  Histological signs of immune reactions against allogeneic solid fetal neural grafts in the mouse cerebellum depend on the MHC locus.

Authors:  I Date; K Kawamura; H Nakashima
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972

9.  Chronic implants of chromaffin tissue into the dopamine-denervated striatum. Effects of NGF on graft survival, fiber growth and rotational behavior.

Authors:  I Strömberg; M Herrera-Marschitz; U Ungerstedt; T Ebendal; L Olson
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

10.  Fine structure of adrenal medullary grafts in the pain modulatory regions of the rat periaqueductal gray.

Authors:  J Sagen; G D Pappas; M J Perlow
Journal:  Exp Brain Res       Date:  1987       Impact factor: 1.972

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