Literature DB >> 25783213

[Molecular diagnostics in melanoma].

R Lang1, J W Bauer, M Laimer.   

Abstract

The molecular landscape of melanoma is changing more rapidly than ever since new molecular technology approaches have made it possible to examine human melanoma for genetic alterations underlying the disease. In recent years, these approaches have identified new familial melanoma susceptibility genes, most of them also conferring risk to other cancers. This has implications for clinical testing and surveillance. Furthermore, molecular testing of melanoma to determine therapeutic eligibility for targeted therapies is now standard of care and should be familiar to the dermatologist.

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Year:  2015        PMID: 25783213     DOI: 10.1007/s00105-015-3614-0

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  25 in total

Review 1.  Melanoma: from mutations to medicine.

Authors:  Hensin Tsao; Lynda Chin; Levi A Garraway; David E Fisher
Journal:  Genes Dev       Date:  2012-06-01       Impact factor: 11.361

2.  Immunohistochemistry is highly sensitive and specific for the detection of NRASQ61R mutation in melanoma.

Authors:  Daniela Massi; Lisa Simi; Elisa Sensi; Gianna Baroni; Gongda Xue; Cristian Scatena; Adele Caldarella; Pamela Pinzani; Gabriella Fontanini; Alessandra Carobbio; Carmelo Urso; Mario Mandalà
Journal:  Mod Pathol       Date:  2014-10-24       Impact factor: 7.842

3.  Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma.

Authors:  Richard W Joseph; Ryan J Sullivan; Robyn Harrell; Katherine Stemke-Hale; David Panka; George Manoukian; Andrew Percy; Roland L Bassett; Chaan S Ng; Laszlo Radvanyi; Patrick Hwu; Michael B Atkins; Michael A Davies
Journal:  J Immunother       Date:  2012-01       Impact factor: 4.456

4.  MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study.

Authors:  Paolo A Ascierto; Dirk Schadendorf; Carola Berking; Sanjiv S Agarwala; Carla Ml van Herpen; Paola Queirolo; Christian U Blank; Axel Hauschild; J Thaddeus Beck; Annie St-Pierre; Faiz Niazi; Simon Wandel; Malte Peters; Angela Zubel; Reinhard Dummer
Journal:  Lancet Oncol       Date:  2013-02-13       Impact factor: 41.316

Review 5.  Genetics of familial melanoma: 20 years after CDKN2A.

Authors:  Lauren G Aoude; Karin A W Wadt; Antonia L Pritchard; Nicholas K Hayward
Journal:  Pigment Cell Melanoma Res       Date:  2015-01-05       Impact factor: 4.693

6.  Mutations in GNA11 in uveal melanoma.

Authors:  Catherine D Van Raamsdonk; Klaus G Griewank; Michelle B Crosby; Maria C Garrido; Swapna Vemula; Thomas Wiesner; Anna C Obenauf; Werner Wackernagel; Gary Green; Nancy Bouvier; M Mert Sozen; Gail Baimukanova; Ritu Roy; Adriana Heguy; Igor Dolgalev; Raya Khanin; Klaus Busam; Michael R Speicher; Joan O'Brien; Boris C Bastian
Journal:  N Engl J Med       Date:  2010-11-17       Impact factor: 91.245

7.  Germline mutations in BAP1 predispose to melanocytic tumors.

Authors:  Thomas Wiesner; Anna C Obenauf; Rajmohan Murali; Isabella Fried; Klaus G Griewank; Peter Ulz; Christian Windpassinger; Werner Wackernagel; Shea Loy; Ingrid Wolf; Agnes Viale; Alex E Lash; Mono Pirun; Nicholas D Socci; Arno Rütten; Gabriele Palmedo; David Abramson; Kenneth Offit; Arthur Ott; Jürgen C Becker; Lorenzo Cerroni; Heinz Kutzner; Boris C Bastian; Michael R Speicher
Journal:  Nat Genet       Date:  2011-08-28       Impact factor: 38.330

8.  POT1 loss-of-function variants predispose to familial melanoma.

Authors:  Carla Daniela Robles-Espinoza; Mark Harland; Andrew J Ramsay; Lauren G Aoude; Víctor Quesada; Zhihao Ding; Karen A Pooley; Antonia L Pritchard; Jessamy C Tiffen; Mia Petljak; Jane M Palmer; Judith Symmons; Peter Johansson; Mitchell S Stark; Michael G Gartside; Helen Snowden; Grant W Montgomery; Nicholas G Martin; Jimmy Z Liu; Jiyeon Choi; Matthew Makowski; Kevin M Brown; Alison M Dunning; Thomas M Keane; Carlos López-Otín; Nelleke A Gruis; Nicholas K Hayward; D Timothy Bishop; Julia A Newton-Bishop; David J Adams
Journal:  Nat Genet       Date:  2014-03-30       Impact factor: 38.330

9.  Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.

Authors:  Lauren G Aoude; Antonia L Pritchard; Carla Daniela Robles-Espinoza; Karin Wadt; Mark Harland; Jiyeon Choi; Michael Gartside; Víctor Quesada; Peter Johansson; Jane M Palmer; Andrew J Ramsay; Xijun Zhang; Kristine Jones; Judith Symmons; Elizabeth A Holland; Helen Schmid; Vanessa Bonazzi; Susan Woods; Ken Dutton-Regester; Mitchell S Stark; Helen Snowden; Remco van Doorn; Grant W Montgomery; Nicholas G Martin; Thomas M Keane; Carlos López-Otín; Anne-Marie Gerdes; Håkan Olsson; Christian Ingvar; Ake Borg; Nelleke A Gruis; Jeffrey M Trent; Göran Jönsson; D Timothy Bishop; Graham J Mann; Julia A Newton-Bishop; Kevin M Brown; David J Adams; Nicholas K Hayward
Journal:  J Natl Cancer Inst       Date:  2014-12-13       Impact factor: 13.506

10.  Survival according to BRAF-V600 tumor mutations--an analysis of 437 patients with primary melanoma.

Authors:  Diana Meckbach; Jürgen Bauer; Annette Pflugfelder; Friedegund Meier; Christian Busch; Thomas K Eigentler; David Capper; Andreas von Deimling; Michel Mittelbronn; Sven Perner; Kristian Ikenberg; Markus Hantschke; Petra Büttner; Claus Garbe; Benjamin Weide
Journal:  PLoS One       Date:  2014-01-24       Impact factor: 3.240

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